DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4562 and qki

DIOPT Version :9

Sequence 1:	NP_001262747.1	Gene:	CG4562 / 42362	FlyBaseID:	FBgn0038740	Length:	1408	Species:	Drosophila melanogaster
Sequence 2:	XP_012818008.1	Gene:	qki / 100038174	XenbaseID:	XB-GENE-486525	Length:	381	Species:	Xenopus tropicalis

Alignment Length:	281	Identity:	57/281 - (20%)
Similarity:	92/281 - (32%)	Gaps:	95/281 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   300 MINYVRTKE--------MNAIRNVNYIRGTLQSFIMFVTRISVFVSLVGFVLLGKLLTAEKAFVI 356
            |:..:.|||        :..:.|...:..:|.:|....|.            |.:||..|.:.|.
Frog    25 MVGEMETKEKPKPTPDYLMQLMNDKKLMSSLPNFCGIFTH------------LERLLDEEISRVR 77

  Fly   357 TAYYNILRN-----TMTVYFPMGISQFAEL-------------------LVSIRRIQTFMLHEET 397
            ...||...|     ..|...|.||....:|                   ::..|.:....|..||
Frog    78 KDMYNDTLNGSNNEKRTSELPDGIGPIVQLQEKLYVPVKEYPDFNFVGRILGPRGLTAKQLEAET 142

  Fly   398 ----KVRDKSEDLDEQKLGKAGLIAEPTVAQTTGVLKPSSRRTSEAEHSIVISKLKAKWDQKNTD 458
                .||.|....|::|             ..|.:|:.|....::.|.    ::.|..|:..|.|
Frog   143 GCKIMVRGKGSMRDKKK-------------AVTNILECSILALNKEEQ----NRGKPNWEHLNED 190

  Fly   459 ----NTLDN------ISLKFKPRQLVAVIGPVGSGKSSLIQAVLGELNPDSGSVKVNGT------ 507
                .|:::      |.||....::..::.|...|:.||.:..|.||      ..:|||
Frog   191 LHVLITVEDAQNRAEIKLKRAVEEVKKLLVPAAEGEDSLKKMQLMEL------AILNGTYRDANL 249

  Fly   508 --------LSYASQEPWLFTG 520
                    |:..:|.|.:.||
Frog   250 KSPALAFSLAATAQAPRIITG 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4562	NP_001262747.1	CFTR_protein	12..1300	CDD:273530	57/281 (20%)
		ABC_membrane	98..367	CDD:294371	16/79 (20%)
		ABCC_MRP_domain1	443..643	CDD:213217	23/102 (23%)
		ABC_membrane	799..1027	CDD:294371
		ABCC_MRP_domain2	1074..1295	CDD:213211
qki	XP_012818008.1	STAR_dimer	34..92	CDD:293152	12/69 (17%)
		SF1_like-KH	108..245	CDD:239088	31/159 (19%)
		PRK04654	179..346	CDD:135173	23/98 (23%)
		Quaking_NLS	354..381	CDD:293159
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0054
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900