Protein Alignment CG4572 and KEX1

DIOPT Version :10

• Sequence 1: NP_650836.1
• Gene: CG4572 / 42360
• FlyBaseID: FBgn0038738
• Length: 482
• Species: Drosophila melanogaster
• Sequence 2: NP_011312.1
• Gene: KEX1 / 852670
• SGDID: S000003171
• Length: 729
• Species: Saccharomyces cerevisiae
• Alignment Length: 441
• Identity: 106/441 - (24%)
• Similarity: 175/441 - (39%)
• Gaps: 114/441 - (25%)

  Fly   102 FFWYFPAEQEPEYA--PVVLWLQGGPGASSLFGLFTENGPLELDGHGKLQKRNYTWSKTHNLIYI 164
            |||.|.........  |:::||.||||.||:.|...|:||..::..|||.....:|....:|::|
Yeast    74 FFWKFTNNDSNGNVDRPLIIWLNGGPGCSSMDGALVESGPFRVNSDGKLYLNEGSWISKGDLLFI 138

  Fly   165 DNPVGTGFSFTEN-DAGYATNEK------DVGRNLHEAVMQLYELFEWSNSSGFWVTGESYAGKY 222
            |.|.|||||..:| |.|.....|      ||.::..:.:...:::|....:....::||||||:|
Yeast   139 DQPTGTGFSVEQNKDEGKIDKNKFDEDLEDVTKHFMDFLENYFKIFPEDLTRKIILSGESYAGQY 203

  Fly   223 VPALAYHI--HKVQNAIETRVYVPLKGVAIGNGLSDPLHQ-LKYGDYLYQLGLIDEHG-----LQ 279
            :|..|..|  |...:.|:...| .||.:.||||..||..| |.|..:..:..||||..     |.
Yeast   204 IPFFANAILNHNKFSKIDGDTY-DLKALLIGNGWIDPNTQSLSYLPFAMEKKLIDESNPNFKHLT 267

  Fly   280 SFH-----------------------------------DAEAKG-AECIKSHDMECAFDVFDSLI 308
            :.|                                   ::..|| |:|:..::    |::.||..
Yeast   268 NAHENCQNLINSASTDEAAHFSYQECENILNLLLSYTRESSQKGTADCLNMYN----FNLKDSYP 328

  Fly   309 NGDLTNGSLFSNLTGYNWYYNYLKTHDDDGANLGEFLQAGATRRAIH---------------VGN 358
            :            .|.||        ..|.:.:.:|........::|               ||.
Yeast   329 S------------CGMNW--------PKDISFVSKFFSTPGVIDSLHLDSDKIDHWKECTNSVGT 373

  Fly   359 KTFHDLDKENKVELHLKKDIMDSVAPWIAELLAHYTVCIYSGQLDIIVAYPLTRNYLNQLKFPGS 423
            |..:.:.|.:   :||...:::|          ...:.:::|..|:|.......:.::.||:.|.
Yeast   374 KLSNPISKPS---IHLLPGLLES----------GIEIVLFNGDKDLICNNKGVLDTIDNLKWGGI 425

  Fly   424 DKYK--------VAPREVWRVGKEVAGYVKHAGHLVEIMVRNAGHMAPHDQ 466
            ..:.        :...:.....:|.:||||:..:|..:.|.||.||.|.|:
Yeast   426 KGFSDDAVSFDWIHKSKSTDDSEEFSGYVKYDRNLTFVSVYNASHMVPFDK 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4572	NP_650836.1	Peptidase_S10	83..479	CDD:459815	106/441 (24%)
KEX1	NP_011312.1	Peptidase_S10	37..484	CDD:459815	106/441 (24%)