Protein Alignment CG4572 and ATG42

DIOPT Version :9

• Sequence 1: NP_650836.1
• Gene: CG4572 / 42360
• FlyBaseID: FBgn0038738
• Length: 482
• Species: Drosophila melanogaster
• Sequence 2: NP_009697.3
• Gene: ATG42 / 852436
• SGDID: S000000343
• Length: 508
• Species: Saccharomyces cerevisiae
• Alignment Length: 487
• Identity: 129/487 - (26%)
• Similarity: 207/487 - (42%)
• Gaps: 108/487 - (22%)

  Fly    46 DGVDPGEPLFLTPLINNASMSKQEVQKLARVVGSQ--FHGVESYSGYLTVDPGFKSNMFFWYFPA 108
            |.::..:|||.|.:   :|:......:|..|..|:  ...|:.:|||:  |.....:.|:|:|.:
Yeast    54 DRLNHDDPLFTTFI---SSVDTDYSLRLRTVDPSKLGIDTVKQWSGYM--DYKDSKHFFYWFFES 113

  Fly   109 EQEPEYAPVVLWLQGGPGASSLFGLFTENGPLELDGHGKLQKRNYTWSKTHNLIYIDNPVGTGFS 173
            ..:|...|::|||.||||.||..||..|.||..:....|.....|:|:...::|:::.|:|.|||
Yeast   114 RNDPANDPIILWLNGGPGCSSFTGLLFELGPSSIGADMKPIHNPYSWNNNASMIFLEQPLGVGFS 178

  Fly   174 FTENDAGYATNEKDVGRNLHEAVMQLYELFEWSNSSGFWVTGESYAGKYVPALAYHIHKVQNAIE 238
            :.:..   .::.|..|::.:..:...:|.|....|:.|.:.||||||.|:|.:|:.| .|:|...
Yeast   179 YGDEK---VSSTKLAGKDAYIFLELFFEAFPHLRSNDFHIAGESYAGHYIPQIAHEI-VVKNPER 239

  Fly   239 TRVYVPLKGVAIGNGLSDPLHQLKY--------GDYLYQLGLIDEHGLQSFHDAE--AKGA---- 289
            |   ..|..|.||||::|||.|..|        |.|         |.:.|..:.|  :|.|
Yeast   240 T---FNLTSVMIGNGITDPLIQADYYEPMACGKGGY---------HPVLSSEECEKMSKAAGRCR 292

  Fly   290 -------------ECIKSHDMECAFDVFDSLINGDL-------------TNGSLFSNLTGYNWYY 328
                         .||.: ...|...:.:..||..|             |:|..::.|...:.|.
Yeast   293 RLNKLCYASKSSLPCIVA-TAYCDSALLEPYINTGLNVYDIRGPCEDNSTDGMCYTGLRYVDQYM 356

  Fly   329 NYLKTHDDDGANLGE-----------FLQAGATRRAIHVGNKTFHDLDKENKVELHLKKDIMDSV 382
            |:.:..:..|:::..           ||..|.       |:|.|..
Yeast   357 NFPEVQETLGSDVHNYSGCDNDVFTGFLFTGD-------GSKPFQQ------------------- 395

  Fly   383 APWIAELLAH-YTVCIYSGQLDIIVAYPLTRNYLNQLKFPGSDKYKVAPREVWRVGKEVA---GY 443
              :|||||.| ..|.||:|..|.|..:.....:.|:|::....:|:......| |.||..   |.
Yeast   396 --YIAELLNHNIPVLIYAGDKDYICNWLGNHAWSNELEWINKRRYQRRMLRPW-VSKETGEELGQ 457

  Fly   444 VKHAGHLVEIMVRNAGHMAPHDQPKWLYMMID 475
            ||:.|....:.:.:||||.|:|||:....|::
Yeast   458 VKNYGPFTFLRIYDAGHMVPYDQPEASLEMVN 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4572	NP_650836.1	Peptidase_S10	83..479	CDD:298660	120/448 (27%)
ATG42	NP_009697.3	Kex1	12..502	CDD:225490	129/487 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	137	1.000	Domainoid score	I1064
eggNOG	1	0.900	-	-		E1_COG2939
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	137	1.000	Inparanoid score	I1200
Isobase	1	0.950	-	0	Normalized mean entropy	S2160
OMA	1	1.010	-	-		QHG54069
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9182
orthoMCL	1	0.900	-	-		OOG6_100109
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R172
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.750