DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4572 and BRS1

DIOPT Version :9

Sequence 1:	NP_650836.1	Gene:	CG4572 / 42360	FlyBaseID:	FBgn0038738	Length:	482	Species:	Drosophila melanogaster
Sequence 2:	NP_194790.1	Gene:	BRS1 / 829184	AraportID:	AT4G30610	Length:	465	Species:	Arabidopsis thaliana

Alignment Length:	470	Identity:	119/470 - (25%)
Similarity:	193/470 - (41%)	Gaps:	92/470 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 LFLTPLINNASMSKQEVQKLARVVGSQFHGVESYSGYLTVDPGFKSNMFFWYFPAEQ-EPEYAPV 117
            |..|...:::|..:||..::..:.|........||||:.|:......:|:|...:.. .|...|:
plant    14 LLSTTFPSSSSSREQEKDRIKALPGQPKVAFSQYSGYVNVNQSHGRALFYWLTESSSPSPHTKPL 78

  Fly   118 VLWLQGGPGASSL-FGLFTENGPLELDGHG-KLQKRNYTWSKTHNLIYIDNPVGTGFSFTENDAG 180
            :|||.||||.||: :|...|.||..::..| .|....:.|:|..||:::::|.|.|:|:|..
plant    79 LLWLNGGPGCSSIAYGASEEIGPFRINKTGSNLYLNKFAWNKDANLLFLESPAGVGYSYTNT--- 140

  Fly   181 YATNEKDVGRNLHEAVMQLYELFEWSNS------SGFWVTGESYAGKYVPALAYHIHKVQNAIET 239
             :::.||.| :...|...|..|.:|.:.      ..|::.||||||.|||.||..|:....|. :
plant   141 -SSDLKDSG-DERTAQDNLIFLIKWLSRFPQYKYRDFYIAGESYAGHYVPQLAKKINDYNKAF-S 202

  Fly   240 RVYVPLKGVAIGNGLSDPLHQLKYGDYLYQLGLID---EHGLQSFHDAEAKGAECIKSHDMECAF 301
            :..:.|||..:||.::|..:.        .:|.:.   .|.:.|  |...|......:..:|...
plant   203 KPIINLKGFLVGNAVTDNQYD--------SIGTVTYWWTHAIIS--DKSYKSILKYCNFTVERVS 257

  Fly   302 DVFDSLIN-------GDLTNGSLFS----------NLTGYNWYYNYLKT---------HDDDGAN 340
            |..|:.:|       ||:...|:::          |.||:  :.....|         :|....:
plant   258 DDCDNAVNYAMNHEFGDIDQYSIYTPTCVAAQQKKNTTGF--FVRMKNTLLRRRLVSGYDPCTES 320

  Fly   341 LGE-FLQAGATRRAIH---------------VGNKTFHDLDKENKVELHLKKDIMDSVAPWIAEL 389
            ..| :......:||:|               |..||:.|.||              ::.|...||
plant   321 YAEKYFNRPDVQRAMHANVTGIRYKWTACSDVLIKTWKDSDK--------------TMLPIYKEL 371

  Fly   390 LAH-YTVCIYSGQLDIIVAYPLTRNYLNQLKFPGSDKYKVAPREVWRVGKEVAGYVKHAGHLVEI 453
            .|. ..:.|:||..|.:|....||..|:.|..|...::     ..|....:|.|:.:....|...
plant   372 AASGLRIWIFSGDTDSVVPVTATRFSLSHLNLPVKTRW-----YPWYTDNQVGGWTEVYKGLTFA 431

  Fly   454 MVRNAGHMAPHDQPK 468
            .||.|||..|..:||
plant   432 TVRGAGHEVPLFEPK 446

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4572	NP_650836.1	Peptidase_S10	83..479	CDD:298660	113/441 (26%)
BRS1	NP_194790.1	Peptidase_S10	37..458	CDD:395361	114/447 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2939
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54069
OrthoDB	1	1.010	-	-		D625787at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100109
Panther	1	1.100	-	-	O	PTHR11802
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.830