Protein Alignment CG4572 and CPVL

DIOPT Version :9

• Sequence 1: NP_650836.1
• Gene: CG4572 / 42360
• FlyBaseID: FBgn0038738
• Length: 482
• Species: Drosophila melanogaster
• Sequence 2: NP_001358193.1
• Gene: CPVL / 54504
• HGNCID: 14399
• Length: 490
• Species: Homo sapiens
• Alignment Length: 455
• Identity: 200/455 - (43%)
• Similarity: 291/455 - (63%)
• Gaps: 31/455 - (6%)

  Fly    49 DPGEPLFLTPLINNASMSKQEVQKLARVVGSQFHG--VESYSGYLTVDPGFKSNMFFWYFPAEQE 111
            |.|:||||||.|....:.|.....|   || .|.|  ::||:|:|||:..:.||:|||:|||:.:
Human    38 DSGQPLFLTPYIEAGKIQKGRELSL---VG-PFPGLNMKSYAGFLTVNKTYNSNLFFWFFPAQIQ 98

  Fly   112 PEYAPVVLWLQGGPGASSLFGLFTENGPLELDGHGKLQKRNYTWSKTHNLIYIDNPVGTGFSFTE 176
            ||.||||||||||||.||:||||.|:||..:..:..|:.|::.|:.|.:::|||||||||||||:
Human    99 PEDAPVVLWLQGGPGGSSMFGLFVEHGPYVVTSNMTLRDRDFPWTTTLSMLYIDNPVGTGFSFTD 163

  Fly   177 NDAGYATNEKDVGRNLHEAVMQLYELFEWSNSSGFWVTGE--------------SYAGKYVPALA 227
            :..|||.||.||.|:|:.|::|.:::|....::.|:||||              |||||||||:|
Human   164 DTHGYAVNEDDVARDLYSALIQFFQIFPEYKNNDFYVTGEHPFVIGHFNICPSQSYAGKYVPAIA 228

  Fly   228 YHIHKVQNAIETRVYVPLKGVAIGNGLSDPLHQL-KYGDYLYQLGLIDEHGLQSFHDAEAKGAEC 291
            :.||.:....|  |.:.|.|:|||:|.|||...: .|.::|||:||:||...:.|.....:..|.
Human   229 HLIHSLNPVRE--VKINLNGIAIGDGYSDPESIIGGYAEFLYQIGLLDEKQKKYFQKQCHECIEH 291

  Fly   292 IKSHDMECAFDVFDSLINGDLTNG-SLFSNLTGYNWYYNYLK-THDDDGANLGEFLQAGATRRAI 354
            |:..:...||::.|.|::||||:. |.|.|:||.:.|||:|: |..:|.....:||.....|:||
Human   292 IRKQNWFEAFEILDKLLDGDLTSDPSYFQNVTGCSNYYNFLRCTEPEDQLYYVKFLSLPEVRQAI 356

  Fly   355 HVGNKTFHDLDKENKVELHLKKDIMDSVAPWIAELLAHYTVCIYSGQLDIIVAYPLTRNYLNQLK 419
            ||||:||:|   ...||.:|::|.:.||.||:.|::.:|.|.||:||||||||..||...|..:.
Human   357 HVGNQTFND---GTIVEKYLREDTVQSVKPWLTEIMNNYKVLIYNGQLDIIVAAALTERSLMGMD 418

  Fly   420 FPGSDKYKVAPREVWRVGK---EVAGYVKHAGHLVEIMVRNAGHMAPHDQPKWLYMMIDHLTHYK 481
            :.||.:||.|.::||::.|   |||||::.||...::::|..||:.|:|||...:.||:...:.|
Human   419 WKGSQEYKKAEKKVWKIFKSDSEVAGYIRQAGDFHQVIIRGGGHILPYDQPLRAFDMINRFIYGK 483

  Fly   482  481
            Human   484  483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4572	NP_650836.1	Peptidase_S10	83..479	CDD:298660	185/417 (44%)
CPVL	NP_001358193.1	Peptidase_S10	69..480	CDD:385311	184/415 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141260
Domainoid	1	1.000	358	1.000	Domainoid score	I980
eggNOG	1	0.900	-	-		E1_COG2939
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H80235
Inparanoid	1	1.050	372	1.000	Inparanoid score	I2126
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54069
OrthoDB	1	1.010	-	-		D274674at33208
OrthoFinder	1	1.000	-	-		FOG0003752
OrthoInspector	1	1.000	-	-		oto89427
orthoMCL	1	0.900	-	-		OOG6_100109
Panther	1	1.100	-	-	LDO	PTHR11802
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1443
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.770