Protein Alignment MFAP1 and Mfap1

DIOPT Version :10

• Sequence 1: NP_005917.2
• Gene: MFAP1 / 4236
• HGNCID: 7032
• Length: 439
• Species: Homo sapiens
• Sequence 2: NP_647679.1
• Gene: Mfap1 / 38256
• FlyBaseID: FBgn0035294
• Length: 478
• Species: Drosophila melanogaster
• Alignment Length: 478
• Identity: 269/478 - (56%)
• Similarity: 339/478 - (70%)
• Gaps: 44/478 - (9%)

Human     1 MSVPSALMKQPPIQSTAGAVPVRNEKGEISMEKVKVKRYVSGKRPDYAPMESSDEEDEEFQFIKK 65
            ||..:|......|||||||:|:||||||:||:||||:||:||||||||..:||.||.::..||..
  Fly     1 MSAATAAAAASGIQSTAGAIPMRNEKGELSMQKVKVQRYISGKRPDYARADSSSEESDDDDFIDT 65

Human    66 AK-----------------------EQEAEPEEQEEDSS--SDPRLRRLQNR--ISEDVE-ERLA 102
            .|                       |:.|..|.||||.:  .|||||||:.|  ..||:| ||..
  Fly    66 RKRLERHKAERHKLELSRQGGSAEGEERAAGEGQEEDDAEVDDPRLRRLRQRPVDMEDMERERRE 130

Human   103 RHRKIVEPEVVGESDS----EVEGDAWRMERED------SSEEEEEEIDDEEIERRRGMMRQRAQ 157
            |||.|.|||:: ||||    |.||....::|..      |..:.:.|:.|.|:|.||..:|.|..
  Fly   131 RHRHIHEPEIM-ESDSEDEEEDEGAQGAIQRGTNKITLASESDTDAELSDTELENRRTKLRSRML 194

Human   158 ERKNEEMEVMEVEDEGRSGEESESE-SEYEEYTDSEDEMEPRLKPVFIRKKDRVTVQEREAEALK 221
            :::.|| ||::.|||.:| |.|||| |||||.|:||::.||||||:|:||:||.|:||:|.||.|
  Fly   195 QQQREE-EVLQKEDEKQS-ESSESESSEYEEETESEEDNEPRLKPLFVRKRDRATIQEKEREAQK 257

Human   222 QKELEQEAKRMAEERRKYTLKIVEEETKKELEENK--RSLAALDALNTDDENDEEEYEAWKVREL 284
            ||:||.||||.|:|||:.||::|||..||:||:.|  .:.|.::.:.|||||||.||||||:|||
  Fly   258 QKQLEAEAKRAAKERRRATLRMVEESVKKDLEKTKPETNEACIEDVCTDDENDEVEYEAWKLREL 322

Human   285 KRIKRDREDREALEKEKAEIERMRNLTEEERRAELRANGKVITNKAVKGKYKFLQKYYHRGAFFM 349
            ||:|||||:|:.:|:||.:|:||||:||||||.|||.|.||:||||.||||||||||||||||::
  Fly   323 KRMKRDREERDNVEREKLDIDRMRNMTEEERRQELRQNPKVVTNKATKGKYKFLQKYYHRGAFYL 387

Human   350 DEDEEVYKRDFSAPTLEDHFNKTILPKVMQVKNFGRSGRTKYTHLVDQDTTSFDSAWGQESAQNT 414
            ||:.:|.||||:..||||||:|||||||||||||||.||||||||||||||.|||.|..||:.|.
  Fly   388 DEENDVLKRDFAQATLEDHFDKTILPKVMQVKNFGRCGRTKYTHLVDQDTTKFDSPWYAESSSNI 452

Human   415 KFFKQKAAGVRDVFERPSAKKRK 437
            ||..:.|.|:|..|::|:..|||
  Fly   453 KFHNEHAGGMRQQFDKPTGSKRK 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFAP1	NP_005917.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..27		14/25 (56%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	39..200		84/199 (42%)
		MFAP1	190..399	CDD:462060	146/210 (70%)
Mfap1	NP_647679.1	MFAP1	233..437	CDD:462060	143/203 (70%)