DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11447 and SPB1

DIOPT Version :9

Sequence 1:	NP_650835.1	Gene:	CG11447 / 42359	FlyBaseID:	FBgn0038737	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	NP_009877.1	Gene:	SPB1 / 850304	SGDID:	S000000559	Length:	841	Species:	Saccharomyces cerevisiae

Alignment Length:	222	Identity:	69/222 - (31%)
Similarity:	105/222 - (47%)	Gaps:	22/222 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 KQQPRNLKGRSKSSQEWLTRQLADPYVEKARMMNYRCRSAFKLLEIDDKYG-ILRPGDTVLECGA 88
            |.|.:|.|||            .|.|...|:...||.||:||:::|::||| .|.....|::..|
Yeast     3 KTQKKNSKGR------------LDRYYYLAKEKGYRARSSFKIIQINEKYGHFLEKSKVVIDLCA 55

  Fly    89 APGSWTQVAVERTNANGKQERAPQGAVFSIDLLHFHAVPGATIFGGMDFTSSLAQKRLREALQDR 153
            |||||.|||.:....|        ..:..:|::....:|....|.. |.|:...:.:||..::..
Yeast    56 APGSWCQVASKLCPVN--------SLIIGVDIVPMKPMPNVITFQS-DITTEDCRSKLRGYMKTW 111

  Fly   154 KVNCVLSDMAPNATGVRMLDQESITNLCYEVLRFALAMSAPQAHLVVKVWDNGDVPKLERDMLRF 218
            |.:.||.|.|||.....:.|..:.:.|..:.|:.|:.........|.|::.:.|..||.....:.
Yeast   112 KADTVLHDGAPNVGLGWVQDAFTQSQLTLQALKLAVENLVVNGTFVTKIFRSKDYNKLIWVFQQL 176

  Fly   219 YEKVKRVKPRASRGDSAEHFLVARNFK 245
            :|||:..||.|||..|||.|:|.:.||
Yeast   177 FEKVEATKPPASRNVSAEIFVVCKGFK 203

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11447	NP_650835.1	RlmE	35..246	CDD:223370	63/212 (30%)
SPB1	NP_009877.1	RlmE	1..206	CDD:223370	69/222 (31%)
		DUF3381	236..383	CDD:403157
		Spb1_C	621..835	CDD:400230
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0293
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810