DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11447 and spb1

DIOPT Version :9

Sequence 1:	NP_650835.1	Gene:	CG11447 / 42359	FlyBaseID:	FBgn0038737	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	NP_593129.1	Gene:	spb1 / 2542112	PomBaseID:	SPAC1687.11	Length:	802	Species:	Schizosaccharomyces pombe

Alignment Length:	221	Identity:	64/221 - (28%)
Similarity:	95/221 - (42%)	Gaps:	21/221 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 KQQPRNLKGRSKSSQEWLTRQLADPYVEKARMMNYRCRSAFKLLEIDDKYGILRPGDTVLECGAA 89
            |.|.:..|||            .|.:.:.|:...||.|:||||::::.||..|.....:::..||
pombe     3 KSQKKTAKGR------------LDKWYKLAKEQGYRSRAAFKLVQLNQKYSFLEKAKVIIDLCAA 55

  Fly    90 PGSWTQVAVERTNANGKQERAPQGAVFSIDLLHFHAVPGATIFGGMDFTSSLAQKRLREALQDRK 154
            ||.|.|||.:...        |...:..:||.....:|....| ..|.||...:.:||..|:..|
pombe    56 PGGWLQVASKTCK--------PGSLIVGVDLAPIKPIPNCHTF-VEDITSDKCRSQLRGYLKTWK 111

  Fly   155 VNCVLSDMAPNATGVRMLDQESITNLCYEVLRFALAMSAPQAHLVVKVWDNGDVPKLERDMLRFY 219
            .:.||.|.|||.....:.|......|....::.|..........|.||:.:.|...|.....:.:
pombe   112 ADVVLHDGAPNVGSAWLQDAYGQAQLVLMSMKLACEFLVAGGTFVTKVFRSRDYNNLLWVFKQLF 176

  Fly   220 EKVKRVKPRASRGDSAEHFLVARNFK 245
            .||:..||.:||..|||.|:|.|.:|
pombe   177 NKVEATKPPSSRNVSAEIFVVCRGYK 202

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11447	NP_650835.1	RlmE	35..246	CDD:223370	59/211 (28%)
spb1	NP_593129.1	RlmE	1..205	CDD:223370	64/221 (29%)
		DUF3381	235..385	CDD:288694
		Spb1_C	588..798	CDD:285075
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0293
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810