Protein Alignment MICU3 and Micu3

DIOPT Version :9

• Sequence 1: NP_001262741.1
• Gene: MICU3 / 42357
• FlyBaseID: FBgn0038735
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_084386.1
• Gene: Micu3 / 78506
• MGIID: 1925756
• Length: 523
• Species: Mus musculus
• Alignment Length: 486
• Identity: 209/486 - (43%)
• Similarity: 272/486 - (55%)
• Gaps: 54/486 - (11%)

  Fly    27 GRSAR-FSSSSSQMGRIPGHKTRR-------LLTIVGGSAVSLAALAAFIKLRSAEN-------- 75
            |.|.| ||......|.:.....||       :....||..|.|.....:...|:..:
Mouse    37 GMSGRPFSCREEDEGAVAEAAWRRRRWGELSIAAAAGGGLVGLVCYQLYGDPRADPSELAAPELE 101

  Fly    76 -----------PVNA----VSLKRRMRDDSELENVKLTARERRFIKFASVEYDDQLYMTPQDFLD 125
                       ||.|    |:..|.:.:|.:|   ..|:|||||..|||:|.:.||:|||.||:.
Mouse   102 DPPRGRGLLPIPVAAAKETVATGRAITEDLDL---YATSRERRFRLFASIECEGQLFMTPYDFIL 163

  Fly   126 SVVEQEPRPRLKRRQLSSDEVDKYKENTPALKKGSTRLFRNLRDKGIVSYTEYLFLLSILTKPKS 190
            :|...||:.....:.||..|:.:....||.:.|||::|||||:::|::|||||||||.|||||.:
Mouse   164 AVTTDEPKFAKTWKSLSKQELSQMLSETPPVWKGSSKLFRNLKERGVISYTEYLFLLCILTKPHA 228

  Fly   191 GFRIAFNMFDTDGNQRVDKDEFLVIISILAGALKDTQNVDPQTKRILSRLVSYDEQSQMTKPMAV 255
            ||||||||||||||:.|||.||||:..|.....:..:....:.||.:.||..|...|.....:
Mouse   229 GFRIAFNMFDTDGNEMVDKKEFLVLQEIFRKKNEKRETKGDEEKRAMLRLQLYGYHSPTNSVL-- 291

  Fly   256 PQAKRGIMERIFSGAWK--EKHGEQEPEEELATPTPLEQNYVNDGEGLQRRHMVATTLQLHFFGK 318
               |....|.:....|.  .:...|....:||.......:.|.|           |||.:|||||
Mouse   292 ---KTDAGELVSRSYWDTLRRSTSQALFSDLAERADDITSLVAD-----------TTLLVHFFGK 342

  Fly   319 RGTGVINYDNFYRFMDNLQTEVLELEFHEFSKGNSVISELDFAKILLRYTYLATDEYDVFLERLL 383
            :|...:|:::||||||||||||||:||..:|.|.:.|||.|||.||||||.:  :...||||.:.
Mouse   343 KGKAELNFEDFYRFMDNLQTEVLEIEFLSYSNGMNTISEEDFAHILLRYTNV--ENTSVFLENVR 405

  Fly   384 ERVKDEKGISFHDFRDFCHFLNNLDDFTIAMRMYTLADRAISKDEFSRAVKICTGYKLSPHLIDT 448
            ..:.:||||:|.:||.|..|||||:||.||:.||..|.|:|.:|||.|||.:.||.||||||::|
Mouse   406 YSISEEKGITFDEFRSFFQFLNNLEDFAIALNMYNFASRSIGQDEFKRAVYVATGLKLSPHLVNT 470

  Fly   449 VFAIFDADGDGLLSYKEFIAIMKDRLHRGFK 479
            ||.|||.|.|..|||||||.||||||||||:
Mouse   471 VFKIFDVDKDDQLSYKEFIGIMKDRLHRGFR 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MICU3	NP_001262741.1	EF-hand_7	421..470	CDD:290234	31/48 (65%)
		EF-hand_8	424..473	CDD:290545	33/48 (69%)
Micu3	NP_084386.1	DUF835	<349..437	CDD:283432	52/89 (58%)
		EF-hand_8	442..495	CDD:290545	35/52 (67%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167841953
Domainoid	1	1.000	76	1.000	Domainoid score	I8965
eggNOG	1	0.900	-	-		E1_KOG2643
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H15058
Inparanoid	1	1.050	343	1.000	Inparanoid score	I2321
Isobase	1	0.950	-	0	Normalized mean entropy	S4754
OMA	1	1.010	-	-		QHG45761
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004781
OrthoInspector	1	1.000	-	-		oto94948
orthoMCL	1	0.900	-	-		OOG6_107718
Panther	1	1.100	-	-	LDO	PTHR12294
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3368
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.710