Protein Alignment MICU3 and Micu2

DIOPT Version :9

• Sequence 1: NP_001262741.1
• Gene: MICU3 / 42357
• FlyBaseID: FBgn0038735
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_082919.1
• Gene: Micu2 / 68514
• MGIID: 1915764
• Length: 432
• Species: Mus musculus
• Alignment Length: 468
• Identity: 169/468 - (36%)
• Similarity: 249/468 - (53%)
• Gaps: 87/468 - (18%)

  Fly    27 GRSARFSSSSSQMGRIPGHKTRRLLTIVGGSAV----SLAALAAFIKLRSAENPVNAVSLKRRMR 87
            ||||..::.        |.:.||.|. .|..||    .|||..|.:.|..|....:...:|...|
Mouse     6 GRSAWLAAW--------GGRLRRGLA-AGRRAVPTRGPLAAAVAGVALAGAGAAWHHGRVKAAAR 61

  Fly    88 DDSELENV---------KLTARERRFIKFASVEYDDQLYMTPQDFLDSVVEQEPRPRLKRRQLSS 143
            :.|...:.         ||:.|::||::|:|:|:|.:.||||:|||.||:.::...:...::|:.
Mouse    62 EGSRTVSAQKNYLGPIEKLSLRKQRFMQFSSLEHDGEYYMTPRDFLFSVMFEQVERKTLVKKLAK 126

  Fly   144 DEVDKYKENTPALKKGSTRLFRNLRDKGIVSYTEYLFLLSILTKPKSGFRIAFNMFDTDGNQRVD 208
            .:::.........:.||| .||:|.|||::|||||||||:|||||.|||.:||.|.|.|||:.::
Mouse   127 KDIEDVLSGIQTARCGST-FFRDLGDKGVISYTEYLFLLTILTKPHSGFHVAFKMLDVDGNEMIE 190

  Fly   209 KDEFLVIISILAGALKDTQNVDPQTKRILSRLVSYDEQSQMTKPMAVPQAKRGIMERIFSGAWKE 273
            :.||:.                      |.:::|..:..:..|
Mouse   191 RKEFVK----------------------LQKIISKQDGFKTVK---------------------- 211

  Fly   274 KHGEQEPEEELATPTPLEQNYVNDGEGLQRRHMVATTLQLHFFGKRGTGVINYDNFYRFMDNLQT 338
                 ..|.|...||..|..             |.||||:.||||||...::|..|.|||:||||
Mouse   212 -----TNETEYQDPTVKEPG-------------VNTTLQVRFFGKRGEKKLHYKEFRRFMENLQT 258

  Fly   339 EVLELEFHEFSKGNSVISELDFAKILLRYTYLATDEYDVFLERLLERVKDEKGISFHDFRDFCHF 403
            ||.|:||.:||||.:.:.:.|||:.||.:|  .|:..|::...:.|::...:.||..:|:.||||
Mouse   259 EVQEMEFLQFSKGLNFMRKEDFAEWLLFFT--NTENKDIYWRNVREKLSVGESISLDEFKSFCHF 321

  Fly   404 LNNLDDFTIAMRMYTLADRAISKDEFSRAVKICTGYKLSPHLIDTVFAIFDADGDGLLSYKEFIA 468
            ..:|:||.|||:|::||.|.:...||.||||:.||.:||.:|:||||.|||.|||..||:.||:.
Mouse   322 TTHLEDFAIAMQMFSLAHRPVRLAEFKRAVKVATGQELSDNLLDTVFKIFDLDGDECLSHGEFLG 386

  Fly   469 IMKDRLHRGFKVS 481
            ::|:|:|||..||
Mouse   387 VLKNRMHRGLWVS 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MICU3	NP_001262741.1	EF-hand_7	421..470	CDD:290234	26/48 (54%)
		EF-hand_8	424..473	CDD:290545	26/48 (54%)
Micu2	NP_082919.1	EF-hand_8	345..391	CDD:290545	26/45 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	175	1.000	Domainoid score	I3647
eggNOG	1	0.900	-	-		E1_KOG2643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D425365at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12294
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.880