Protein Alignment MICU3 and micu-1

DIOPT Version :9

• Sequence 1: NP_001262741.1
• Gene: MICU3 / 42357
• FlyBaseID: FBgn0038735
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_001255723.1
• Gene: micu-1 / 178287
• WormBaseID: WBGene00013462
• Length: 534
• Species: Caenorhabditis elegans
• Alignment Length: 543
• Identity: 148/543 - (27%)
• Similarity: 234/543 - (43%)
• Gaps: 145/543 - (26%)

  Fly    25 GVGRSARFSSSSSQMGRIPGHKTRRL------LTIVGGSAVSLAALAAFIK--LRSAENPVN-AV 80
            |||.| .:|||..|.........|:|      |.|.|  .|.|.:...::|  ::||..|.. ..
 Worm    72 GVGYS-HYSSSVYQHRPYIWPPLRKLYHWNYALVIAG--MVILMSDFEWLKDQIKSASLPFRPEA 133

  Fly    81 SLKRRMRD-DSELENV-------KLTARERRFIKFASVEYDDQL--------------------- 116
            |.|..:.: :.|:|.|       ||..||||.|     ||:|:|
 Worm   134 SQKEEVTESNGEVEEVKEKPKKKKLGFRERRII-----EYEDRLRLYSTPDKIFRYFATLKIIDP 193

  Fly   117 ---------YMTPQDFLDSVVEQEPRPRLKRRQLSSDEVDKYKENTPALKK-----GSTRLFRNL 167
                     :|||:|||.|......:||  |..|     |.:|...|...|     ....:|..|
 Worm   194 NEDSGRFEVFMTPEDFLRSFTPGVMQPR--RWGL-----DSFKNYNPEKHKRHKFSDPDSIFYKL 251

  Fly   168 RDKGIVSYTEYLFLLSILTKPKSGFRIAFNMFDTDGNQRVDKDEFLVIISILAGALKDTQNVDPQ 232
            .:.|::::::||||:::|:...:.|.:||.:||.|||..:||:||..:..::
 Worm   252 GENGLINFSDYLFLMTLLSTSHADFALAFKIFDVDGNGALDKEEFTKVQQLI------------- 303

  Fly   233 TKRILSRLVSYDEQSQMTKPMAVPQAKRGIMERIFSGAWKEKHGEQEPEEELATPTPLEQNYVND 297
                         .||.|    |.|..|                      :..||   .|::
 Worm   304 -------------MSQTT----VGQRHR----------------------DHITP---NQSF--- 323

  Fly   298 GEGLQRRHMVATTLQLHFFGKRGTGVINYDNFYRFMDNLQTEVLELEFHE---FSKGNSVISELD 359
                  |....:.|:.:||||.|.|.::.:.|..|.:.||.::|::||..   ....:.:|:|..
 Worm   324 ------RVETNSALETYFFGKDGKGSLSSEKFIEFQERLQHDILKMEFERRDALDNPDGLINEDS 382

  Fly   360 FAKILLRYTYLATDEYDVFLERLLERVKDE--KGISFHDFRDFCHFLNNLDDFTIAMRMYTLADR 422
            ||::||.:..:...:....|:|:..|.|.|  |||||.:.:.|..||.::||..||:..:.:|..
 Worm   383 FAQLLLLHAQINEKKQKHMLKRVKRRFKGENLKGISFGETKAFFEFLYHIDDVDIALHFHKMAGM 447

  Fly   423 AISKDEFSR-AVKICTGYKLSPHLIDTVFAIFDADGDGLLSYKEFIAIMKDRLHRGF---KVSGR 483
            :|......| |||: ||..||.|::|.|..:||.:.||.||::|.:|:|:.|:.||.   :.:|.
 Worm   448 SIDAKLLQRVAVKV-TGIPLSDHVVDVVITLFDDNLDGKLSHEEMVAVMRRRMRRGLERPRDTGL 511

  Fly   484 FFDYNEALD----AYDEPDYPLF 502
            |..::..|:    ||.....|.:
 Worm   512 FRLFDAVLECGKRAYHASPLPFY 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MICU3	NP_001262741.1	EF-hand_7	421..470	CDD:290234	20/49 (41%)
		EF-hand_8	424..473	CDD:290545	21/49 (43%)
micu-1	NP_001255723.1	FRQ1	<254..352	CDD:227455	36/161 (22%)
		EFh	<254..298	CDD:298682	18/43 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D425365at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920