DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bnl and FGF11

DIOPT Version :9

Sequence 1:	NP_732452.1	Gene:	bnl / 42356	FlyBaseID:	FBgn0014135	Length:	770	Species:	Drosophila melanogaster
Sequence 2:	NP_004103.1	Gene:	FGF11 / 2256	HGNCID:	3667	Length:	225	Species:	Homo sapiens

Alignment Length:	135	Identity:	42/135 - (31%)
Similarity:	64/135 - (47%)	Gaps:	12/135 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   260 LQILRDGVVNGTQDENSEFTILQRSTVDVGRIKLQSVATCLYLCMDACGVPYGSKDFTDDCVFNE 324
            ||...||.:.||.::.|.||......|.:..:.:||.....|:.|:|.|:.|.|..||.:|.|.|
Human    83 LQANPDGSIQGTPEDTSSFTHFNLIPVGLRVVTIQSAKLGHYMAMNAEGLLYSSPHFTAECRFKE 147

  Fly   325 NMGLQNYNTYSSTYHSQAR--RVFYLALNGSGQ------PRRTQIPASRSLGKL---STYTNAIT 378
            .:....|..|:|..:.|.|  |.:||.|:..||      .::|: .|:..|.||   :.|.....
Human   148 CVFENYYVLYASALYRQRRSGRAWYLGLDKEGQVMKGNRVKKTK-AAAHFLPKLLEVAMYQEPSL 211

  Fly   379 ETVPQ 383
            .:||:
Human   212 HSVPE 216

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bnl	NP_732452.1	FGF	247..376	CDD:214665	40/126 (32%)
FGF11	NP_004103.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..28
FGF11	NP_004103.1	FGF	69..199	CDD:214665	37/116 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	83	1.000	Domainoid score	I8338
eggNOG	1	0.900	-	-		E1_KOG3885
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm41236
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11486
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	6	5.870