Protein Alignment bnl and FGF5

DIOPT Version :9

• Sequence 1: NP_732452.1
• Gene: bnl / 42356
• FlyBaseID: FBgn0014135
• Length: 770
• Species: Drosophila melanogaster
• Sequence 2: NP_004455.2
• Gene: FGF5 / 2250
• HGNCID: 3683
• Length: 268
• Species: Homo sapiens
• Alignment Length: 241
• Identity: 74/241 - (30%)
• Similarity: 115/241 - (47%)
• Gaps: 36/241 - (14%)

  Fly   193 QPMSPA--DNNFIGSKSKRLSNPRSSLNINSSSSNTPISNLDRNERSTVPQSHLAWT---SRKIQ 252
            || .||  |.|..||.|::.|   ||...:||:|::|.::|. ::.|.:.||...|:   .|...
Human    31 QP-GPAATDRNPRGSSSRQSS---SSAMSSSSASSSPAASLG-SQGSGLEQSSFQWSPSGRRTGS 90

  Fly   253 LYIKNRI---LQILRDGVVNGTQDENSEFTILQRSTVDVGRIKLQSVATCLYLCMDACGVPYGSK 314
            ||.:..|   |||..||.|||:.:.|. .::|:...|..|.:.::.|.:..:|.|...|..:.|.
Human    91 LYCRVGIGFHLQIYPDGKVNGSHEANM-LSVLEIFAVSQGIVGIRGVFSNKFLAMSKKGKLHASA 154

  Fly   315 DFTDDCVFNENMGLQNYNTYSSTYH--SQARRVFYLALNGSGQPRRTQIPASRSLGKLSTY---- 373
            .|||||.|.|.....:||||:|..|  .:..|.:|:|||..|:.:|...|..:. ..:||:
Human   155 KFTDDCKFRERFQENSYNTYASAIHRTEKTGREWYVALNKRGKAKRGCSPRVKP-QHISTHFLPR 218

  Fly   374 -------TNAITETVPQERVE--------QLIAKNFGANRVKHGVR 404
                   ..:.|.|||:::..        .|.|.....|.||:.::
Human   219 FKQSEQPELSFTVTVPEKKKPPSPIKPKIPLSAPRKNTNSVKYRLK 264

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bnl	NP_732452.1	FGF	247..376	CDD:214665	44/147 (30%)
FGF5	NP_004455.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	26..81		20/54 (37%)
		FGF	87..216	CDD:395115	44/130 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	233..255		4/21 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	83	1.000	Domainoid score	I8338
eggNOG	1	0.900	-	-		E1_KOG3885
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm41236
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11486
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	6	5.870