DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bnl and FGF2

DIOPT Version :9

Sequence 1:	NP_732452.1	Gene:	bnl / 42356	FlyBaseID:	FBgn0014135	Length:	770	Species:	Drosophila melanogaster
Sequence 2:	NP_001997.5	Gene:	FGF2 / 2247	HGNCID:	3676	Length:	288	Species:	Homo sapiens

Alignment Length:	118	Identity:	39/118 - (33%)
Similarity:	56/118 - (47%)	Gaps:	9/118 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   240 PQSHLAWTSRKIQLYIKNR--ILQILRDGVVNGTQDENSEFTILQRSTVDVGRIKLQSVATCLYL 302
            |..|.....|   ||.||.  .|:|..||.|:|.::::.....||....:.|.:.::.|....||
Human   155 PPGHFKDPKR---LYCKNGGFFLRIHPDGRVDGVREKSDPHIKLQLQAEERGVVSIKGVCANRYL 216

  Fly   303 CMDACGVPYGSKDFTDDCVFNENMGLQNYNTYSSTYHSQARRVFYLALNGSGQ 355
            .|...|....||..||:|.|.|.:...|||||.|..::.    :|:||..:||
Human   217 AMKEDGRLLASKCVTDECFFFERLESNNYNTYRSRKYTS----WYVALKRTGQ 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bnl	NP_732452.1	FGF	247..376	CDD:214665	37/111 (33%)
FGF2	NP_001997.5	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..133
		FGF	161..282	CDD:278592	37/112 (33%)
		Cell attachment site, atypical. /evidence=ECO:0000255	179..181		1/1 (100%)
		Cell attachment site, atypical. /evidence=ECO:0000255	221..223		0/1 (0%)
		Heparin-binding. /evidence=ECO:0000250	261..277		2/5 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3885
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11486
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.910