DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment bnl and Fgf13

DIOPT Version :9

Sequence 1:	NP_732452.1	Gene:	bnl / 42356	FlyBaseID:	FBgn0014135	Length:	770	Species:	Drosophila melanogaster
Sequence 2:	NP_001277343.1	Gene:	Fgf13 / 14168	MGIID:	109178	Length:	255	Species:	Mus musculus

Alignment Length:	240	Identity:	67/240 - (27%)
Similarity:	98/240 - (40%)	Gaps:	53/240 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   227 PISNLDRNERSTVPQSHLAWTSRKIQLYIKNRI-LQILRDGVVNGTQDENSEFTILQRSTVDVGR 290
            |:..:...|.:...:..|.....|  ||.:... ||:..||.::||:||:|.:|:.....|.:..
Mouse    59 PLKQVHHKENTEPEEPQLKGIVTK--LYSRQGYHLQLQADGTIDGTKDEDSTYTLFNLIPVGLRV 121

  Fly   291 IKLQSVATCLYLCMDACGVPYGSKDFTDDCVFNENMGLQNYNTYSSTYH--SQARRVFYLALNGS 353
            :.:|.|.|.|||.|::.|..|.|:.||.:|.|.|::....|.||||..:  .|:.|.:||.||..
Mouse   122 VAIQGVQTKLYLAMNSEGYLYTSEHFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKE 186

  Fly   354 GQPRRTQIPASRSLGKLSTYTNAITETVPQERVEQLIAKNFGANRVKHGVRQLCDTGKPLIELID 418
            |:                                  |.|   .|.||..........|||    .
Mouse   187 GE----------------------------------IMK---GNHVKKNKPAAHFLPKPL----K 210

  Fly   419 VARFKAPP-HCSSNTSGSSSSISSSSSSSS------KSSSNSSSS 456
            ||.:|.|. |..:..|.|.|...:.|.|.|      ||.|::.|:
Mouse   211 VAMYKEPSLHDLTEFSRSGSGTPTKSRSVSGVLNGGKSMSHNEST 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bnl	NP_732452.1	FGF	247..376	CDD:214665	41/131 (31%)
Fgf13	NP_001277343.1	FGF	77..207	CDD:214665	46/168 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	83	1.000	Domainoid score	I8324
eggNOG	1	0.900	-	-		E1_KOG3885
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm43297
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11486
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.960