DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11453 and AAE12

DIOPT Version :9

Sequence 1:	NP_650832.1	Gene:	CG11453 / 42355	FlyBaseID:	FBgn0038734	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_176764.1	Gene:	AAE12 / 842901	AraportID:	AT1G65890	Length:	578	Species:	Arabidopsis thaliana

Alignment Length:	548	Identity:	136/548 - (24%)
Similarity:	224/548 - (40%)	Gaps:	113/548 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 RIAQQLKAMGLKQDDVVGIVGTNTTYLMPVVLGCLLNGTPFHAVSPWQDEDTIKHLFSITRPKLI 131
            |:|..|.::.:.::|||.:|..||..:..:.....:.|...:.::...|..:|..:....:||::
plant    51 RLAASLISLNIGKNDVVSVVAPNTPAMYEMHFAVPMAGAVLNPINTRLDATSIAAILRHAKPKIL 115

  Fly   132 FCDGKCFQRLS-IIARILKSHVYTLKDHRLGMP-----RVEDLLEPTTAELYYVPETLLLGGDHT 190
            |. .:.|:.|: .|.::|.|     :|..|.:|     .::.....::.|..|  |.|:..|:.|
plant   116 FI-YRSFEPLAREILQLLSS-----EDSNLNLPVIFIHEIDFPKRVSSEESDY--ECLIQRGEPT 172

  Fly   191 VAILC----------------TSGTTGLPKAVCISN-SACLFDFGFVTGQD-----VLLSFSTID 233
            ..:|.                |||||..||.|.||: .|.|.....:.|.:     |.|
plant   173 PLLLARMFCIQDEHDPISLNYTSGTTADPKGVVISHRGAYLSTLSAIIGWEMGTCPVYL------ 231

  Fly   234 WSAGMFNMLFSCCHGST----------RIITDRPYTPEYMIQLVEKYKVTLLTVVPQQVASLLKT 288
            |:..||:     |:|.|          ..:..|..|...:.:.:|.:.||.:..||.....|||.
plant   232 WTLPMFH-----CNGWTFTWGTAARGGTSVCMRHVTAPEIYKNIEMHNVTHMCCVPTVFNILLKG 291

  Fly   289 PTLNKQRLASIRFVSVGGGSCYVANLLKLQEFLITGQISYGYALTECGG---------------- 337
            .:|:....:....|..||.....|.:.|:|.  :..|:.:.|.|||..|
plant   292 NSLDLSHRSGPVHVLTGGSPPPAALVKKVQR--LGFQVMHAYGLTEATGPVLFCEWQDEWNRLPE 354

  Fly   338 -----VAANMGVAKPSSVGRIVPGVRVKILDEA----GRSLGHGETGEILVHNGKVWNGYYANPN 393
                 :.|..|:   |.:|.....||.|...|:    |:::     |||::....:..||..||.
plant   355 NQQMELKARQGL---SILGLTEVDVRNKETQESVPRDGKTM-----GEIVMKGSSIMKGYLKNPK 411

  Fly   394 ESKRMQDYQ----GWFHTGDMGYFDNENYLHIVERKEDLLRFHGAQYSPQEIEQVIAELPDVIEA 454
            .:     |:    ||.::||:|....:.::.|.:|.:|::...|...|..|:|.:|.:.|.|:|.
plant   412 AT-----YEAFKHGWLNSGDVGVIHPDGHVEIKDRSKDIIISGGENISSVEVENIIYKYPKVLET 471

  Fly   455 CVFGLWNEVDGDPAAAAVVKIPGSR----------LTEMDIVEYVAKRLVVDHKQLHCGVFFLPE 509
            .|..:.:...|:...|.||...|..          ..|.|::||..:.|  .|......|.||.|
plant   472 AVVAMPHPTWGETPCAFVVLEKGETNNEDREDKLVTKERDLIEYCRENL--PHFMCPRKVVFLDE 534

  Fly   510 LPKTGSGKVLRQQARDQALGKKWADHGN 537
            |||.|:||:|:.:.||.|.|....|..|
plant   535 LPKNGNGKILKPKLRDIAKGLVAEDEVN 562

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11453	NP_650832.1	CaiC	18..530	CDD:223395	133/539 (25%)
CG11453	NP_650832.1	Firefly_Luc_like	46..519	CDD:213279	129/528 (24%)
AAE12	NP_176764.1	PLN03102	1..578	CDD:215576	136/548 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810