DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11453 and BZO1

DIOPT Version :9

Sequence 1:	NP_650832.1	Gene:	CG11453 / 42355	FlyBaseID:	FBgn0038734	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_176763.1	Gene:	BZO1 / 842900	AraportID:	AT1G65880	Length:	580	Species:	Arabidopsis thaliana

Alignment Length:	538	Identity:	137/538 - (25%)
Similarity:	224/538 - (41%)	Gaps:	108/538 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 RIAQQLKAMGLKQDDVVGIVGTNTTYLMPVVLGCLLNGTPFHAVSPWQDEDTIKHLFSITRPKLI 131
            |:|..|.::.:.::|||.::..||..|..:.....:.|...:.::...|..:|..:....:||::
plant    51 RLAASLISLNISKNDVVSVMAPNTPALYEMHFAVPMAGAVLNPINTRLDATSIAAILRHAKPKIL 115

  Fly   132 FCDGKCFQRLSIIARILKSHVYTLKDHRLGMPRV----EDLLEPTTA---ELYYVPETLLLGGDH 189
            |.| :.|:.|   || ...|:.:.:|..|.:|.:    .|.  |..|   ||.|  |.|:..|:.
plant   116 FLD-RSFEAL---AR-ESLHLLSSEDSNLNLPVIFIHENDF--PKRASFEELDY--ECLIQRGEP 171

  Fly   190 T----------------VAILCTSGTTGLPKAVCISN-SACLFDFGFVTGQD-----VLLSFSTI 232
            |                :::..|||||..||.|.||: .|.|.....:.|.:     |.|
plant   172 TPSMVARMFRIQDEHDPISLNYTSGTTADPKGVVISHRGAYLCTLSAIIGWEMGTCPVYL----- 231

  Fly   233 DWSAGMFNMLFSCCHGST----------RIITDRPYTPEYMIQLVEKYKVTLLTVVPQQVASLLK 287
             |:..||:     |:|.|          ..:..|..|...:.:.:|.:.||.:..||.....|||
plant   232 -WTLPMFH-----CNGWTFTWGTAARGGTSVCMRHVTAPEIYKNIEMHNVTHMCCVPTVFNILLK 290

  Fly   288 TPTLNKQRLASIRFVSVGGGSCYVANLLKLQEFLITGQISYGYALTECGG--------------- 337
            ..:|:....:....|..||.....|.:.|:|.  :..|:.:.|..||..|
plant   291 GNSLDLSPRSGPVHVLTGGSPPPAALVKKVQR--LGFQVMHAYGQTEATGPILFCEWQDEWNRLP 353

  Fly   338 ------VAANMGVAKPSSVGRIVPGVRVKILDEAGRSLGHGET-GEILVHNGKVWNGYYANPNES 395
                  :.|..|:   |.:|  :..|.||..:....:...|:| ||||:....:..||..||..:
plant   354 ENQQMELKARQGI---SILG--LADVDVKNKETQKSAPRDGKTMGEILIKGSSIMKGYLKNPKAT 413

  Fly   396 KRMQDYQGWFHTGDMGYFDNENYLHIVERKEDLLRFHGAQYSPQEIEQVIAELPDVIEACVFGL- 459
            .....: ||.:|||:|....:.::.|.:|.:|::...|...|..|:|.|:.:.|.|:|..|..:
plant   414 FEAFKH-GWLNTGDVGVIHPDGHVEIKDRSKDIIISGGENISSVEVENVLYKYPKVLETAVVAMP 477

  Fly   460 ---WNEVDGDPAAAAVV----------KIPGSRLTEMDIVEYVAKRLVVDHKQLHCGVFFLPELP 511
               |.|.   |.|..|:          ::...:..|.:::||..:.|  .|......|.||.|||
plant   478 HPTWGET---PCAFVVLEKSETTIKEDRVDKFQTRERNLIEYCRENL--PHFMCPRKVVFLEELP 537

  Fly   512 KTGSGKVLRQQARDQALG 529
            |.|:||:|:.:.||.|.|
plant   538 KNGNGKILKPKLRDIAKG 555

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11453	NP_650832.1	CaiC	18..530	CDD:223395	137/538 (25%)
CG11453	NP_650832.1	Firefly_Luc_like	46..519	CDD:213279	132/526 (25%)
BZO1	NP_176763.1	PLN03102	1..580	CDD:215576	137/538 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810