DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11453 and OPCL1

DIOPT Version :9

Sequence 1:	NP_650832.1	Gene:	CG11453 / 42355	FlyBaseID:	FBgn0038734	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_564115.1	Gene:	OPCL1 / 838639	AraportID:	AT1G20510	Length:	546	Species:	Arabidopsis thaliana

Alignment Length:	562	Identity:	144/562 - (25%)
Similarity:	257/562 - (45%)	Gaps:	81/562 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 NRSTTQFDKYTKIWSGPRPA----SFFDADCSIGKILFAFMRNHPNSICQISDTEGTALTNGEAI 62
            |.::|.:.|.|.|...|.|:    :|..:....|:|.|            |..:.|..||..|..
plant    12 NSNSTFYSKRTPIPLPPNPSLDVTTFISSQAHRGRIAF------------IDASTGQNLTFTELW 64

  Fly    63 TFAIRIAQQLKAMGLKQDDVVGIVGTNTTYLMPVV------LGCLLNGTPFHAVSPWQDEDTIKH 121
            .....:|..|..:|:::..||.::..| :.|.|||      ||.::..|     :|....:.|..
plant    65 RAVESVADCLSEIGIRKGHVVLLLSPN-SILFPVVCLSVMSLGAIITTT-----NPLNTSNEIAK 123

  Fly   122 LFSITRPKLIFCDGKCFQRLSIIARILKSHVYTLKDHRL----GMPRVEDLL--EPTTAELYYVP 180
            ....:.|.|.|...:...::|..|:  |..:..:.:.|:    .:.|:.:::  ||:...   |.
plant   124 QIKDSNPVLAFTTSQLLPKISAAAK--KLPIVLMDEERVDSVGDVRRLVEMMKKEPSGNR---VK 183

  Fly   181 ETLLLGGDHTVAILCTSGTTGLPKAVCISN-------SACLFDFGFVTGQDVLLS-------FST 231
            |.  :..|.|..:|.:|||||:.|.|..|:       ...:..||...|:...:.       :..
plant   184 ER--VDQDDTATLLYSSGTTGMSKGVISSHRNLIAMVQTIVNRFGSDDGEQRFICTVPMFHIYGL 246

  Fly   232 IDWSAGMFNMLFSCCHGSTRIITDRPYTPEYMIQLVEKYKVTLLTVVPQQVASLLKTPTLNKQR- 295
            ..::.|:.      .:|||.|:..: :....|:..:.||:.|.|.:||..:.:::......|.:
plant   247 AAFATGLL------AYGSTIIVLSK-FEMHEMMSAIGKYQATSLPLVPPILVAMVNGADQIKAKY 304

  Fly   296 -LASIRFVSVGGGSCYVANLLK-----LQEFLITGQISYGYALTECGGVAANMGVAKPS----SV 350
             |:|:..|..||     |.|.|     ..|...|.:|..||.|||..|:.|:....:.|    :.
plant   305 DLSSMHTVLCGG-----APLSKEVTEGFAEKYPTVKILQGYGLTESTGIGASTDTVEESRRYGTA 364

  Fly   351 GRIVPGVRVKILDE-AGRSLGHGETGEILVHNGKVWNGYYANPNESKRMQDYQGWFHTGDMGYFD 414
            |::...:..:|:|. .|:.||..:|||:.:....:..||::|...:....|.:||..|||:.|.|
plant   365 GKLSASMEGRIVDPVTGQILGPKQTGELWLKGPSIMKGYFSNEEATSSTLDSEGWLRTGDLCYID 429

  Fly   415 NENYLHIVERKEDLLRFHGAQYSPQEIEQVIAELPDVIEACVFGLWNEVDGDPAAAAVVKIPGSR 479
            .:.::.:|:|.::|:::.|.|.:|.|:|.::...|::.:|.|....::..|....|.||:..||.
plant   430 EDGFIFVVDRLKELIKYKGYQVAPAELEALLLTHPEITDAAVIPFPDKEVGQFPMAYVVRKTGSS 494

  Fly   480 LTEMDIVEYVAKRLVVDHKQLHCGVFFLPELPKTGSGKVLRQ 521
            |:|..|:|:|||: |..:|::. .|.|:..:||..|||:||:
plant   495 LSEKTIMEFVAKQ-VAPYKRIR-KVAFVSSIPKNPSGKILRK 534

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11453	NP_650832.1	CaiC	18..530	CDD:223395	139/546 (25%)
CG11453	NP_650832.1	Firefly_Luc_like	46..519	CDD:213279	131/510 (26%)
OPCL1	NP_564115.1	4CL	26..536	CDD:341230	139/548 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24096
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920