DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11453 and AT1G20500

DIOPT Version :9

Sequence 1:	NP_650832.1	Gene:	CG11453 / 42355	FlyBaseID:	FBgn0038734	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_173474.5	Gene:	AT1G20500 / 838638	AraportID:	AT1G20500	Length:	550	Species:	Arabidopsis thaliana

Alignment Length:	540	Identity:	137/540 - (25%)
Similarity:	236/540 - (43%)	Gaps:	77/540 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 FAFMRNHPNSICQISDTEGTALTNGEAITFAIRIAQQL-KAMGLKQDDVVGIVGTNTTYLMPVVL 98
            |...:.|......|....|..||..:......|:|..| ..:|:::.|||.|:..|:.::..|.|
plant    43 FISSQPHRGKTAFIDAATGQCLTFSDLWRAVDRVADCLYHEVGIRRGDVVLILSPNSIFIPVVCL 107

  Fly    99 GCLLNGTPFHAVSPWQDEDTIKHLFSITRPKLIF-----------------CDGKCFQRLSIIAR 146
            ..:..|..|...:.......|....:.:.|.|:|                 .|.:.:|.|:...|
plant   108 SVMSLGAVFTTANTLNTSGEISKQIADSNPTLVFTTRQLAPKLPVAISVVLTDDEVYQELTSAIR 172

  Fly   147 ILKSHVYTLKDHRLGMPRVEDLLEPTTAELYYVPETLLLGGDHTVAILCTSGTTGLPKAVC---- 207
            ::......:|....|. ||.|.:..                |.|..:|.:|||||..|.|.
plant   173 VVGILSEMVKKEPSGQ-RVRDRVNQ----------------DDTAMMLYSSGTTGPSKGVISSHR 220

  Fly   208 ---------ISNSACLFDFGFVTGQDVLLSFSTIDWSAGMFNMLFSCCHGSTRIITDRPYTPEYM 263
                     ||::....|. |:....:..::..:.::.|...:      |||.:|. |.:....|
plant   221 NLTAHVARFISDNLKRDDI-FICTVPMFHTYGLLTFAMGTVAL------GSTVVIL-RRFQLHDM 277

  Fly   264 IQLVEKYKVTLLTVVPQQVASLLKTPTLNKQR--LASIRFVSVGGGSCYVANLLK------LQEF 320
            :..|||::.|.|.:.|..:.:::....|.|.:  |:|::.|..||     |.|.|      |:::
plant   278 MDAVEKHRATALALAPPVLVAMINDADLIKAKYDLSSLKTVRCGG-----APLSKEVTEGFLEKY 337

  Fly   321 LITGQISYGYALTECGGVAANMGVAKPS----SVGRIVPGVRVKILD-EAGRSLGHGETGEILVH 380
             .|..|..||||||..|..|....|:.|    :.|.:...|..:|:| ..||.:|..:|||:.:.
plant   338 -PTVDILQGYALTESNGGGAFTNSAEESRRYGTAGTLTSDVEARIVDPNTGRFMGINQTGELWLK 401

  Fly   381 NGKVWNGYYANPNESKRMQDYQGWFHTGDMGYFDNENYLHIVERKEDLLRFHGAQYSPQEIEQVI 445
            ...:..||:.|...:....:.:||..|||:.|.|.:.:|.:|:|.::|:::.|.|..|.|:|.::
plant   402 GPSISKGYFKNQEATNETINLEGWLKTGDLCYIDEDGFLFVVDRLKELIKYKGYQVPPAELEALL 466

  Fly   446 AELPDVIEACVFGLWNEVDGDPAAAAVVKIPGSRLTEMDIVEYVAKRLVVDHKQLHCGVFFLPEL 510
            ...||:::|.|....::..|....|.||:...|.|:|..::::::|: |..:|::. .|.|:..:
plant   467 ITHPDILDAAVIPFPDKEAGQYPMAYVVRKHESNLSEKQVIDFISKQ-VAPYKKIR-KVSFINSI 529

  Fly   511 PKTGSGKVLRQQARDQALGK 530
            |||.|||.||:.....|..|
plant   530 PKTASGKTLRKDLIKLATSK 549

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11453	NP_650832.1	CaiC	18..530	CDD:223395	136/538 (25%)
CG11453	NP_650832.1	Firefly_Luc_like	46..519	CDD:213279	131/516 (25%)
AT1G20500	NP_173474.5	PLN02574	16..542	CDD:215312	135/531 (25%)
AT1G20500	NP_173474.5	4CL	32..542	CDD:213272	135/531 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24096
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920