DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11453 and AT5G63380

DIOPT Version :9

Sequence 1:	NP_650832.1	Gene:	CG11453 / 42355	FlyBaseID:	FBgn0038734	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_201143.1	Gene:	AT5G63380 / 836457	AraportID:	AT5G63380	Length:	562	Species:	Arabidopsis thaliana

Alignment Length:	563	Identity:	155/563 - (27%)
Similarity:	260/563 - (46%)	Gaps:	78/563 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 FDKYTKIWSGPRPA-SFFDADCSIGKILFAFMRNHPNSICQISDTEGTALTNGEAITFAI----- 66
            ||:.|.|:...||: |....|..:....||.      |:...|....||..|.||:|:.:
plant    17 FDQRTGIYHSLRPSLSLPPIDQPLSAAEFAL------SLLLKSSPPATAGKNIEALTYLVNSSSG 75

  Fly    67 ------RIAQQLKAMGLK-QDDVVGIVGTNTTYLM-------PVVLGCLLN-GTPFHAVSPWQDE 116
                  .:.::::::.:. ::....:...|..:::       ||:...|:: |......:|...|
plant    76 DNLTYGELLRRVRSLAVSLRERFPSLASRNVAFILSPSSLDIPVLYLALMSIGVVVSPANPIGSE 140

  Fly   117 DTIKHLFSITRPKLIFCDGKCFQRLSIIARILKSHVYTLKDHRLGMPRVEDLLEPTTAELYYV-- 179
            ..:.|...::.|.:.|...:..::|...:..|.:                 :|..:|..|.::
plant   141 SEVSHQVEVSEPVIAFATSQTVKKLQSSSLPLGT-----------------VLMDSTEFLSWLNR 188

  Fly   180 -------PETLLLGGDHTVAILCTSGTTGLPKAVCISNSACLFDFGFVTGQDVLLSFSTIDWSAG 237
                   |..:.:......|||.:|||||..|.|.:::...:.... |:.|..|......| ..|
plant   189 SDSSSVNPFQVQVNQSDPAAILFSSGTTGRVKGVLLTHRNLIASTA-VSHQRTLQDPVNYD-RVG 251

  Fly   238 MFN-----------MLFSCCHGSTRIITDRPYTPEYMIQLVEKYKVTLLTVVPQQVASLLKTPTL 291
            :|:           |:.:...|.|.::..| :..|.|.:.|||||||.:.|.|..:.:|:|:...
plant   252 LFSLPLFHVFGFMMMIRAISLGETLVLLGR-FELEAMFKAVEKYKVTGMPVSPPLIVALVKSELT 315

  Fly   292 NKQRLASIRFVSVGGGSC--YVANLLKLQEFLITGQISYGYALTECGGVAANM----GVAKPSSV 350
            .|..|.|:|.:..||...  .:|...| |:|... .|..||.|||..|.||:.    .:.|..||
plant   316 KKYDLRSLRSLGCGGAPLGKDIAERFK-QKFPDV-DIVQGYGLTESSGPAASTFGPEEMVKYGSV 378

  Fly   351 GRIVPGVRVKILD-EAGRSLGHGETGEILVHNGKVWNGYYANPNESKRMQDYQGWFHTGDMGYFD 414
            |||...:..||:| ..|.||..|:|||:.:....:..||..|...|....|.:||..|||:.|||
plant   379 GRISENMEAKIVDPSTGESLPPGKTGELWLRGPVIMKGYVGNEKASAETVDKEGWLKTGDLCYFD 443

  Fly   415 NENYLHIVERKEDLLRFHGAQYSPQEIEQVIAELPDVIEACVFGLWNEVDGDPAAAAVVKIPGSR 479
            :|::|:||:|.::|:::...|..|.|:||::...||||:|.|....:|..|:...|.:|:.|||.
plant   444 SEDFLYIVDRLKELIKYKAYQVPPVELEQILHSNPDVIDAAVVPFPDEDAGEIPMAFIVRKPGSN 508

  Fly   480 LTEMDIVEYVAKRLVVDHKQLHCGVFFLPELPKTGSGKVLRQQ 522
            |.|..|:::|||: |..:|::. .|.|:..:||..:||:||::
plant   509 LNEAQIIDFVAKQ-VTPYKKVR-RVAFINAIPKNPAGKILRRE 549

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11453	NP_650832.1	CaiC	18..530	CDD:223395	151/553 (27%)
CG11453	NP_650832.1	Firefly_Luc_like	46..519	CDD:213279	142/519 (27%)
AT5G63380	NP_201143.1	PLN02574	17..562	CDD:215312	155/563 (28%)
AT5G63380	NP_201143.1	4CL	48..550	CDD:213272	145/526 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24096
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920