DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11453 and 4CL5

DIOPT Version :9

Sequence 1:	NP_650832.1	Gene:	CG11453 / 42355	FlyBaseID:	FBgn0038734	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_188760.3	Gene:	4CL5 / 821677	AraportID:	AT3G21230	Length:	570	Species:	Arabidopsis thaliana

Alignment Length:	535	Identity:	155/535 - (28%)
Similarity:	256/535 - (47%)	Gaps:	87/535 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 NSICQISDTEGTALTNGEAITFAIRIAQQLKAMGLKQDDVVGIVGTNT-----TYLMPVVLGCL- 101
            ::.|.|....|..||..:..|...|||..:..:|::..|||.::..|:     ::|....||.:
plant    61 STTCIIDGATGRILTYADVQTNMRRIAAGIHRLGIRHGDVVMLLLPNSPEFALSFLAVAYLGAVS 125

  Fly   102 LNGTPFHAVSPWQDEDTIKHLFSITRPKLIFCDGKCFQRLSIIARILKSHVYTLK---------- 156
            ....||:                 |:|::.........::.|..:.|...:..||
plant   126 TTANPFY-----------------TQPEIAKQAKASAAKMIITKKCLVDKLTNLKNDGVLIVCLD 173

  Fly   157 -DHRLGMPRVEDLLEPTTAELYYVPETLLL----GGDHTVAILCTSGTTGLPKAVCISNSACLFD 216
             |...|:....|....:..||....||.||    ..:.|||:..:||||||||.|.|::.
plant   174 DDGDNGVVSSSDDGCVSFTELTQADETELLKPKISPEDTVAMPYSSGTTGLPKGVMITHK----- 233

  Fly   217 FGFVT-------GQDVLLSFSTID---WSAGMFN-------MLFSCCHGSTRIITDRPYTPEYMI 264
             |.||       |::..|:|:..|   ....||:       ||.:...|:..:|..| :....::
plant   234 -GLVTSIAQKVDGENPNLNFTANDVILCFLPMFHIYALDALMLSAMRTGAALLIVPR-FELNLVM 296

  Fly   265 QLVEKYKVTLLTVVPQQVASLLKTPTLNKQRLASIRFVSVGGGSCYVANLLK-LQEFL------- 321
            :|:::||||::.|.|..|.:.:|:|...:..|:|:|.:..|     .|.|.| |::.:
plant   297 ELIQRYKVTVVPVAPPVVLAFIKSPETERYDLSSVRIMLSG-----AATLKKELEDAVRLKFPNA 356

  Fly   322 ITGQISYGYALTECGGVAANMGVA------KPSSVGRIVPGVRVKILD-EAGRSLGHGETGEILV 379
            |.||   ||.:||.|.||.::..|      |..:.|.::....:|::| |.|.||...::|||.|
plant   357 IFGQ---GYGMTESGTVAKSLAFAKNPFKTKSGACGTVIRNAEMKVVDTETGISLPRNKSGEICV 418

  Fly   380 HNGKVWNGYYANPNESKRMQDYQGWFHTGDMGYFDNENYLHIVERKEDLLRFHGAQYSPQEIEQV 444
            ...::..||..:|..:.|..|..||.||||:|:.|:::.:.||:|.::|::|.|.|.:|.|:|.:
plant   419 RGHQLMKGYLNDPEATARTIDKDGWLHTGDIGFVDDDDEIFIVDRLKELIKFKGYQVAPAELEAL 483

  Fly   445 IAELPDVIEACVFGLWNEVDGDPAAAAVVKIPGSRLTEMDIVEYVAKRLVVDHKQLHCGVFFLPE 509
            :...|.:.:|.|..:.:||..:...|.|.:..||:|||.|:..||.|: ||.:|::.. |||:..
plant   484 LISHPSIDDAAVVAMKDEVADEVPVAFVARSQGSQLTEDDVKSYVNKQ-VVHYKRIKM-VFFIEV 546

  Fly   510 LPKTGSGKVLRQQAR 524
            :||..|||:||:..|
plant   547 IPKAVSGKILRKDLR 561

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11453	NP_650832.1	CaiC	18..530	CDD:223395	155/535 (29%)
CG11453	NP_650832.1	Firefly_Luc_like	46..519	CDD:213279	152/525 (29%)
4CL5	NP_188760.3	PLN02246	20..567	CDD:215137	155/535 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24096
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920