DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11453 and acsf3

DIOPT Version :9

Sequence 1:	NP_650832.1	Gene:	CG11453 / 42355	FlyBaseID:	FBgn0038734	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	XP_021329817.1	Gene:	acsf3 / 562292	ZFINID:	ZDB-GENE-121026-3	Length:	579	Species:	Danio rerio

Alignment Length:	515	Identity:	109/515 - (21%)
Similarity:	203/515 - (39%)	Gaps:	101/515 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 KAMGLKQDDVVG-----IVGTNTTYLMPVVLGCLLNG--TPFHAVSPWQDEDTIKHLFSITRPKL 130
            ||:..:..|:.|     :...:.:|.:......:..|  .|.:...|..:   ::::.|.::..|
Zfish    93 KALTCQSGDLQGKRISFLCANDASYTVAQWASWMCGGIAVPLYRKHPLSE---LEYVISDSQSSL 154

  Fly   131 IFCDGKCFQRLSIIARILKSHVYTLKD--HRLGMPRVEDLLEPTTAEL---YYVPETLLLG-GDH 189
            :...              :|.|.||:.  .:||:|.::  |..|:::.   ..:||.::.. .:.
Zfish   155 LVAG--------------QSFVDTLEPLAQKLGLPCLK--LPATSSQFEDTQTLPEDMISDWAER 203

  Fly   190 TVAILCTSGTTGLPKAVCISNSACLFDFGFVTG---------QDVLLSFSTIDWSAGMFNMLFSC 245
            ...::.||||||.||.|..::|:..   ..|.|         .||:|....:....|:.|.|.
Zfish   204 PAMLIYTSGTTGRPKGVLHTHSSLQ---AMVQGLVSEWAWHKDDVILHTLPLHHVHGIVNKLM-- 263

  Fly   246 CH---GSTRIITDRPYTPEYMIQLV-------EKYKVTLLTVVPQQVASLLK-------TPTLN- 292
            |.   |:|.|:     .|::..|.|       :...|.:...||...:.|::       .|.:.
Zfish   264 CPLWVGATCIM-----LPDFSAQKVWEQLICSKSPMVNVFMAVPTIYSKLIEYYDQHFTQPQVQD 323

  Fly   293 ------KQRLASIRFVSVGGGSCYVANLLKLQEFLITGQISYGYALTECGGVAAN--MGVAKPSS 349
                  |:|:.    :.|.|.:.....:|:....:....:...|.:||.|...:|  .|...|.:
Zfish   324 FIRAVCKERIR----LMVSGSAALPQPVLERWAEITDHVLLERYGMTEIGMALSNSYKGPRVPGA 384

  Fly   350 VGRIVPGVRVKILDEA------GRSLG-------HGETGEILVHNGKVWNGYYANPNESKRMQDY 401
            ||..:|||.|:|:..:      |.|.|       .|:.||:||....|:..|:..|.|::.....
Zfish   385 VGVPLPGVEVRIMMNSSIVIAEGTSKGTQVKAGLEGKEGELLVRGSSVFQKYWNKPQETEESFTE 449

  Fly   402 QGWFHTGDMGYFDNENYLHIVERKEDLLRFHGAQYSPQEIEQVIAELPDVIEACVFGLWNEVDGD 466
            ..||.|||...:.:..|..:.....|:::..|.:.|..::|:.:...||:.:..|.|..:...|.
Zfish   450 DRWFKTGDTALYRDGVYWIMGRTSVDIIKSGGYKISALDVERHLLAHPDITDVAVIGAPDATWGQ 514

  Fly   467 PAAAAVVKIPGSRLTEMDIVEYVAKRLVVDHKQLHCGVFFLPELPKTGSGKV-----LRQ 521
            ...|.|....|..:...|:..:..:.:.  ...:..|:..:.::|:...|||     |||
Zfish   515 KVTAVVQMRKGKTMILSDLKAWAREHMA--SYSIPTGLILVEDMPRNQMGKVNKKDLLRQ 572

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11453	NP_650832.1	CaiC	18..530	CDD:223395	109/515 (21%)
CG11453	NP_650832.1	Firefly_Luc_like	46..519	CDD:213279	106/511 (21%)
acsf3	XP_021329817.1	MCS	64..566	CDD:213307	106/507 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900