DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11453 and slc27a4

DIOPT Version :9

Sequence 1:	NP_650832.1	Gene:	CG11453 / 42355	FlyBaseID:	FBgn0038734	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_001017737.1	Gene:	slc27a4 / 550432	ZFINID:	ZDB-GENE-050417-248	Length:	643	Species:	Danio rerio

Alignment Length:	569	Identity:	129/569 - (22%)
Similarity:	221/569 - (38%)	Gaps:	114/569 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 SIGKILFAFMRNHPNSICQISDTEGTALTNGEAITFAIRIAQQLKAMGLKQDDVVGIVGTNTTYL 93
            ::.|:....::.:.|....|.:......:..|...::.|:|..|...|.::.|||.:...|....
Zfish    75 TVPKLFAKSVKKYGNKTALIFEGTDEKWSFKELDEYSNRVANFLLQQGFREGDVVALFMENRHQY 139

  Fly    94 MPVVLGCLLNGTPFHAVSPWQDEDTIKHLFSITRPKLI-----FCDGKCFQRLSI--IARILKSH 151
            :.:.||....|.....::.....:.:.|..:|:..|.:     ..:..|....|:  ..::..|.
Zfish   140 VGLWLGMAKIGVEAALINFNLRLEALVHCVNISSAKAVVFGSELTEAMCEVHSSMGKTVKLFVSG 204

  Fly   152 VYTLKDHRLGMPRVEDLLEPT------------TAELYYVPETLLLGGDHTVAILCTSGTTGLPK 204
            .:..|...:|...::.|||.|            |..|:|:               .||||||:||
Zfish   205 EWDPKRVPVGTEHLDPLLETTSTIQPKQPDRSFTDRLFYI---------------YTSGTTGMPK 254

  Fly   205 AVCISNS-----ACLFDFGF-VTGQDVLLSFSTIDWSAG-MFNMLFSCCHGSTRIITDRPYTPEY 262
            |..:.:|     |.|..:|| :..:|||.....:..||| :..:.....||.|.:|..:....::
Zfish   255 AAIVVHSRYYRMAALVYYGFRMKPEDVLYDCLPLYHSAGNIVGIGQGLIHGMTVVIRKKFSASKF 319

  Fly   263 MIQLVEKYKVTLLTVVPQQVASLLKTPTLNKQRLASIRFVSVGGG---SCYVANLLKLQEF---L 321
            ....: ||..|::..:.:....||..|..:.:|...:| :::|.|   |.:       :||   .
Zfish   320 WDDCI-KYNCTIVQYIGEICRYLLNQPRKDTERKHKVR-MALGNGLRQSIW-------EEFTNRF 375

  Fly   322 ITGQISYGYALTECGGVAANMGVAKPSSVG---RIVP---GVRVKILDEAGRSL----------- 369
            ...||:..|..|||.....|.. .|..:.|   ||:|   .:|:..:||....|
Zfish   376 NVPQIAEFYGATECNCSLGNFD-NKTGACGFNSRILPYVYPIRLVKVDEETMELIRGPDGVCIPC 439

  Fly   370 GHGETGEI---LVHNGKV--WNGYYANPNESKRMQDYQGWFHTGDMGY-------FDNENYLHIV 422
            |.||.|::   ::.|..:  ::||......:|::.  |..|..||..|       .|:..|::..
Zfish   440 GPGEPGQLVGRIIQNDPLRRFDGYVNQTATNKKIA--QDVFKKGDSAYLSGDVLVMDDFGYMYFR 502

  Fly   423 ERKEDLLRFHGAQYSPQEIEQVIAELPDVIEACVFGLWNEVDGDPAAAAVVKIPG---------- 477
            :|..|..|:.|...|..|:|..::.|.|:.:..|:|:  ||.|....|.:..|..
Zfish   503 DRTGDTFRWKGENVSTTEVEGTLSRLLDMKDVVVYGV--EVPGAEGKAGMAAIADPENNTDLAKF 565

  Fly   478 SRLTEMDIVEYVAKRLVVDHKQLHCGVF--FLPELPKTGSGKVLRQQAR 524
            ||..|..:..|...            ||  ||||:.|||:.|..:...|
Zfish   566 SRDLEKALPPYARP------------VFLRFLPEVDKTGTFKFQKTDMR 602

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11453	NP_650832.1	CaiC	18..530	CDD:223395	129/569 (23%)
CG11453	NP_650832.1	Firefly_Luc_like	46..519	CDD:213279	126/545 (23%)
slc27a4	NP_001017737.1	PRK08279	73..643	CDD:236217	129/569 (23%)
slc27a4	NP_001017737.1	hsFATP4_like	99..608	CDD:213305	126/545 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583203
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930