DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11453 and CG6178

DIOPT Version :9

Sequence 1:	NP_650832.1	Gene:	CG11453 / 42355	FlyBaseID:	FBgn0038734	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_651221.1	Gene:	CG6178 / 42867	FlyBaseID:	FBgn0039156	Length:	544	Species:	Drosophila melanogaster

Alignment Length:	508	Identity:	141/508 - (27%)
Similarity:	247/508 - (48%)	Gaps:	71/508 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 IRIAQQLKAMGLKQDDVVGIVGTNT-TYLMPVVLGCLLNGTPFHAVSP----WQDEDTIKHLFSI 125
            :|:|..|:.:|:||:||||:...|: .:.:.:..|..:..|    |:|    :.|.: :.|..::
  Fly    63 VRLAYILQKLGVKQNDVVGLSSENSVNFALAMFAGLAVGAT----VAPLNVTYSDRE-VDHAINL 122

  Fly   126 TRPKLIFCDGKCFQRLSIIA---RILK------------SHVYTLKDHRLGMPRVEDLLEPTTAE 175
            ::||:||.......|::.:|   :.:|            .::|.||:      .:||....|..:
  Fly   123 SKPKIIFASKITIDRVAKVASKNKFVKGIIALSGTSKKFKNIYDLKE------LMEDEKFKTQPD 181

  Fly   176 LYYVPETLLLGGDHTVA-ILCTSGTTGLPKAVCISNSACLFDFG------FVTGQDVLLSFSTID 233
             :..|..   ..|..|: |:|:||||||||.|.::....|....      .:..::|.| .:.|.
  Fly   182 -FTSPAA---NKDEDVSLIVCSSGTTGLPKGVQLTQMNLLATLDSQIQPTVIPMEEVTL-LTVIP 241

  Fly   234 W--SAGMFNMLFSCCHGSTRIITDRPYTPEY----MIQLVEKYKVTLLTVVPQQVASLLKTPTLN 292
            |  :.|...::.:.|.|: |::    |.|::    .:..:|||:|.:..:||..:..|.|.|.::
  Fly   242 WFHAFGCLTLITTACVGA-RLV----YLPKFEEKLFLSAIEKYRVMMAFMVPPLMVFLAKHPIVD 301

  Fly   293 KQRLASIRFVSVGGGSCYVANLLKLQEFLITGQISYGYALTE--CGGVAANMGVAKPSSVGRIVP 355
            |..|:|:..:..|..........:::|.:....|..||.|:|  ...:..|....||.|||.:..
  Fly   302 KYDLSSLMVLLCGAAPLSRETEDQIKERIGVPFIRQGYGLSESTLSVLVQNDEFCKPGSVGVLKV 366

  Fly   356 GVRVKILD-EAGRSLGHGETGEILVHNGKVWNGYYANPNESKRMQDYQGWFHTGDMGYFDNENYL 419
            |:..|::| :.|:.||..|.||:......:..||..: .:|.:.....||.||||:||:|::...
  Fly   367 GIYAKVIDPDTGKLLGANERGELCFKGDGIMKGYIGD-TKSTQTAIKDGWLHTGDIGYYDDDFEF 430

  Fly   420 HIVERKEDLLRFHGAQYSPQEIEQVIAELPDVIEACVFGLWNEVDGDPAAAAVVKIPGSRLTEMD 484
            .||:|.::|:::.|.|..|.|||.::.....:.:|.|.|..:|..|:...|.|||....:|||.:
  Fly   431 FIVDRIKELIKYKGYQVPPAEIEALLLTNDKIKDAAVIGKPDEEAGELPLAFVVKQANVQLTENE 495

  Fly   485 IVEYV------AKRLVVDHKQLHCGVFFLPELPKTGSGKVLRQQARDQALGKK 531
            ::::|      |||       |..||.|:.|:||..|||:||:..|:....:|
  Fly   496 VIQFVNDNASPAKR-------LRGGVIFVDEIPKNPSGKILRRILREMLKKQK 541

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11453	NP_650832.1	CaiC	18..530	CDD:223395	140/505 (28%)
CG11453	NP_650832.1	Firefly_Luc_like	46..519	CDD:213279	137/494 (28%)
CG6178	NP_651221.1	PLN02246	26..537	CDD:215137	140/502 (28%)
CG6178	NP_651221.1	Firefly_Luc_like	43..529	CDD:213279	137/494 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24096
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920