DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11453 and Fatp3

DIOPT Version :9

Sequence 1:	NP_650832.1	Gene:	CG11453 / 42355	FlyBaseID:	FBgn0038734	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_726437.2	Gene:	Fatp3 / 37887	FlyBaseID:	FBgn0034999	Length:	687	Species:	Drosophila melanogaster

Alignment Length:	580	Identity:	122/580 - (21%)
Similarity:	221/580 - (38%)	Gaps:	144/580 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 RNHPNSICQISDTEGTALTNGEAITFAIRIAQQLKAMGLKQDDVVGIVGTNTTYLMPVV-LGCLL 102
            |..|...|.:.|..  .|:..||:.|:.:||......||::.|.|.:: ..|....|.: ||...
  Fly   124 RRRPKKTCFVMDDR--HLSFAEALEFSQKIAGYFSDRGLERGDCVALL-METRLEYPCIWLGLSQ 185

  Fly   103 NGTPFHAVSPWQDEDTIKHLFSITRPKLIFCDGKCFQRLSIIARILKSH------VYTLKD---- 157
            .|.....::.....:::.|...:...|.:....   :.|.::..:.:..      :|...|
  Fly   186 LGVITALINSNLRGESLLHSIKVANAKALIVGS---ELLDVLVSLREKEQLDEVPIYQYTDDEVR 247

  Fly   158 ----HRLGMPRVEDLLEP-TTAELYYVPETLLLGGDHT-VAILCTSGTTGLPKAVCISNSACLFD 216
                |.| :|...||:.. .|.:...:|..:..|...: :..:.||||||||||..|:|...||
  Fly   248 GVAGHDL-LPGAVDLVTALKTQKKLELPSAVCPGEARSKLLYVYTSGTTGLPKAAVITNLRFLF- 310

  Fly   217 FGFVTGQDVLLSFSTID----------WSAGMFNMLFSCCHGSTRII------------TDR--- 256
              ...|...:|..|:.|          .:.|:..:..:..:|||.::            .||
  Fly   311 --MSAGSYYMLKMSSDDVVYDPLPLYHTAGGIVGVGNAILNGSTVVLRKKFSARNFWLDCDRHNC 373

  Fly   257 ----------------PYTPEYMIQLVEKYKVTLL---TVVPQ---QVASLLKTPTLNK------ 293
                            .|:|:.     :|:.:.|:   .:.||   |.......|.:.:
  Fly   374 TVAQYIGELCRYLLATSYSPDQ-----QKHNLRLMYGNGLRPQIWSQFVRRFGIPHIGEIYGATE 433

  Fly   294 ---------QRLASIRFVSVGGGSCYVANLLKLQEFLITGQI---SYGYALTECGGVAANMGVAK 346
                     .|:.:|.||.|.|.|.|...:|:..|:  ||::   |.|:.: .|          :
  Fly   434 GNSNLINITNRVGAIGFVPVYGSSLYPVQVLRCDEY--TGELLKDSKGHCI-RC----------Q 485

  Fly   347 PSSVGRIVPGVRVKILDEAGRSLG--HGETGEILVHNGKVWNGYYAN--PNESKRMQDY----QG 403
            |...|.:|..|      :|.|::.  ||                ||:  .:|.|.:::.    ..
  Fly   486 PGQAGLLVGKV------DARRAVSAFHG----------------YADKGASEQKLLRNVFTSGDV 528

  Fly   404 WFHTGDMGYFDNENYLHIVERKEDLLRFHGAQYSPQEIEQVIAELPDVIEACVFGLW-NEVDGDP 467
            :|::|||...|...|.:..:|..|..|:.|...:.||:|.:|.....:.:..|:|:. ..|:|..
  Fly   529 FFNSGDMVVRDILGYFYFKDRTGDTFRWRGENVATQEVEAIITNCVGLEDCVVYGVQIPHVEGKA 593

  Fly   468 AAAAVVKIPGSRLTEMDIVEYVAKRLVVDHKQLHCGVFFLPELPKTGSGKVLRQQARDQA 527
            ..||:|  ...|..:||.:..|.:..:..:.: ...:..|.|:|:|.:.|:.:::...:|
  Fly   594 GMAAIV--DPERKVDMDYLSVVLRGSLPPYAR-PLFIRLLDEIPRTATFKLKKRELAKEA 650

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11453	NP_650832.1	CaiC	18..530	CDD:223395	122/580 (21%)
CG11453	NP_650832.1	Firefly_Luc_like	46..519	CDD:213279	119/563 (21%)
Fatp3	NP_726437.2	PRK08279	90..684	CDD:236217	122/580 (21%)
Fatp3	NP_726437.2	hsFATP4_like	136..653	CDD:213305	118/568 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452213
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840