DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11453 and Acsm5

DIOPT Version :9

Sequence 1:	NP_650832.1	Gene:	CG11453 / 42355	FlyBaseID:	FBgn0038734	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_001014184.3	Gene:	Acsm5 / 361637	RGDID:	1309578	Length:	578	Species:	Rattus norvegicus

Alignment Length:	493	Identity:	129/493 - (26%)
Similarity:	211/493 - (42%)	Gaps:	58/493 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 AMGLKQDDVVGIVGTNTTYLMPVVLGCLLNG-TPFHAVSPWQDEDTIKHLFSITRPKLIFCDGKC 137
            |.|||..|.:.:|..........::.|:..| .....:|....:| :|:.....|.|.|......
  Rat   108 ACGLKPGDRLMLVLPRLPEWWLTIVACMRTGVVMIPGISQLTQKD-LKYRLQAARVKSIITSDAL 171

  Fly   138 FQRLSIIAR---ILKSHVYTLKDHRLGMPRVEDLLEPTTAELYYVPETLLL---GGDHTVAILCT 196
            ...:..|:.   .|:|.:......|.|.....:||...:      ||...|   .|| ::||..|
  Rat   172 APHVDAISADCPSLQSRLLVSDTSRPGWINFRELLRVAS------PEHNCLRTRSGD-SMAIYFT 229

  Fly   197 SGTTGLPKAVCISNSACLFDFGFV---------TGQDVLLSFSTIDWSAGMFNMLFSCCHGSTRI 252
            |||||.||.|  .:|.|.:..|||         |..|:..:.:...|....:.:..:..:|:...
  Rat   230 SGTTGTPKMV--EHSQCSYGLGFVASGRRLMALTESDIFWNTTDTGWVKAAWTLFSAWANGACVF 292

  Fly   253 ITDRPYT-PEYMIQLVEKYKVTLLTVVPQQVASLLKTPTLNKQRLASIRFVSVGGGSCY--VANL 314
            :.:.|.. .:.::..:.::.:|.:..|| .:..||....|.:.:...:|....||.:..  |.:.
  Rat   293 VHELPQVDAQTILNTLCRFPITTICCVP-TLFRLLVQEDLTRYKFQCLRHCLAGGEALNSDVRDK 356

  Fly   315 LKLQEFLITG-QISYGYALTE----CGGVAANMGVAKPSSVGRIVPGVRVKILDEAGRSLGHGET 374
            .|.|    || :|..||..:|    ||....:  ..|..|:|:..|...|:|:||.|..|..|:.
  Rat   357 WKNQ----TGLEIHEGYGQSETVLICGNFRGS--TIKSGSMGKASPPYDVQIVDEEGNVLPPGKE 415

  Fly   375 GEILVHNGK-----VWNGYYANPNESKRMQDYQGWFH-TGDMGYFDNENYLHIVERKEDLLRFHG 433
            |.|.:....     ::|.|..||.::...:  ||.|: |||..:.|.:.|...|.|.:|::....
  Rat   416 GNIAIRIKPTRPFCLFNCYLDNPEKTAASE--QGDFYITGDRAHMDEDGYFWFVGRNDDVINSSS 478

  Fly   434 AQYSPQEIEQVIAELPDVIEACVFGLWNEVDGDPAAAAVVKIPG------SRLTEMDIVEYVAKR 492
            .:..|.|:|..:||.|.|:|:.|....:.:.|:...|.:|..|.      ..||. ::.|:| |.
  Rat   479 YRIGPVEVESALAEHPAVLESAVVSSPDPIRGEVVKAFIVLSPAYVSHDPEALTR-ELQEHV-KT 541

  Fly   493 LVVDHKQLHCGVFFLPELPKTGSGKVLRQQARDQALGK 530
            :...:|... .|.|:.|||||.|||:||.:.|:|..|:
  Rat   542 VTAPYKYPR-KVAFISELPKTVSGKILRSKLRNQEWGR 578

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11453	NP_650832.1	CaiC	18..530	CDD:223395	128/491 (26%)
CG11453	NP_650832.1	Firefly_Luc_like	46..519	CDD:213279	124/480 (26%)
Acsm5	NP_001014184.3	AFD_class_I	48..576	CDD:418409	128/489 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010