DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11453 and Slc27a2

DIOPT Version :9

Sequence 1:	NP_650832.1	Gene:	CG11453 / 42355	FlyBaseID:	FBgn0038734	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_036108.2	Gene:	Slc27a2 / 26458	MGIID:	1347099	Length:	620	Species:	Mus musculus

Alignment Length:	510	Identity:	106/510 - (20%)
Similarity:	187/510 - (36%)	Gaps:	151/510 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 LTNGEAITFA------IRIAQQL-KAMGLKQDDVVGI-VGTNTTYLMPVVLGCLLNGTPFHAVSP 112
            |...|.:|:|      .::|:.| ..:||:|.|.|.: :|....|:. :.||.|..|.|...::
Mouse    73 LFRDETLTYAQVDRRSNQVARALHDQLGLRQGDCVALFMGNEPAYVW-IWLGLLKLGCPMACLN- 135

  Fly   113 WQDEDTIKHLFSITRPKLIFCDGKCFQRLSIIARILKSHVYTLKDHRLGMPRVEDLLE---PT-- 172
                      ::|....|:.|...|.      |::|           |..|.:::.:|   ||
Mouse   136 ----------YNIRAKSLLHCFQCCG------AKVL-----------LASPDLQEAVEEVLPTLK 173

  Fly   173 --TAELYYVPETLLLGGDHTV--------------------------AILCTSGTTGLPKAVCIS 209
              ...::||..|....|..|:                          ..:.||||||||||..|:
Mouse   174 KDAVSVFYVSRTSNTNGVDTILDKVDGVSAEPTPESWRSEVTFTTPAVYIYTSGTTGLPKAATIN 238

  Fly   210 NSACLFDFGF-----VTGQDVLLSFSTIDWSAGMFNMLFSCCHGSTRIITDRPYTPEYMIQLVEK 269
            :....:..|.     :|.|||:.:...:..||.:...|..|......:.....::.........|
Mouse   239 HHRLWYGTGLAMSSGITAQDVIYTTMPLYHSAALMIGLHGCIVVGATLALRSKFSASQFWDDCRK 303

  Fly   270 YKVTLLTVVPQQVASLLKTPTLNKQRLASIRFVSVGGGSCYVANLLKLQEFLITGQI------SY 328
            |.||::..:.:.:..|..||.....|...:: .::|.|              :.|.:      .:
Mouse   304 YNVTVIQYIGELLRYLCNTPQKPNDRDHKVK-KALGNG--------------LRGDVWREFIKRF 353

  Fly   329 G-------YALTECGGVAANMG-VAKPSSVGRIVPG-------VRVKIL------DEAGR----- 367
            |       ||.||     .|:| |..|..:|.:...       .|.:::      ||..|
Mouse   354 GDIHVYEFYASTE-----GNIGFVNYPRKIGAVGRANYLQRKVARYELIKYDVEKDEPVRDANGY 413

  Fly   368 --SLGHGETGEILVHNGKV--WNGYYA--NPNESKRMQDY--QG--WFHTGDMGYFDNENYLHIV 422
              .:..||.|.::....::  :.||..  ...|.|:::|.  :|  :|::||:...|.||:::..
Mouse   414 CIKVPKGEVGLLVCKITQLTPFIGYAGGKTQTEKKKLRDVFKKGDIYFNSGDLLMIDRENFVYFH 478

  Fly   423 ERKEDLLRFHGAQYSPQEIEQVIAELPDVIEACVFGLWNEVDGDPAAAAVVKIPG 477
            :|..|..|:.|...:..|:..::..:..|.|..|:|              |.:||
Mouse   479 DRVGDTFRWKGENVATTEVADIVGLVDFVEEVNVYG--------------VPVPG 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11453	NP_650832.1	CaiC	18..530	CDD:223395	106/510 (21%)
CG11453	NP_650832.1	Firefly_Luc_like	46..519	CDD:213279	106/510 (21%)
Slc27a2	NP_036108.2	hsFATP2a_ACSVL_like	74..610	CDD:341261	105/509 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839146
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930