DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11453 and SPCC1827.03c

DIOPT Version :9

Sequence 1:	NP_650832.1	Gene:	CG11453 / 42355	FlyBaseID:	FBgn0038734	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_001342732.1	Gene:	SPCC1827.03c / 2539253	PomBaseID:	SPCC1827.03c	Length:	512	Species:	Schizosaccharomyces pombe

Alignment Length:	541	Identity:	139/541 - (25%)
Similarity:	211/541 - (39%)	Gaps:	116/541 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 DTEGTALT----NGEAITFAIRIA-----QQLKAMGLKQDDVVGIVGTNTTYLMPVVLGCLLNG- 104
            |....||.    |.|.....:|||     :|:.::|:|..|.|.|              .:.||
pombe    13 DASARALVAPSLNAELSFSELRIAIMDLQRQIASLGIKVGDPVNI--------------AIPNGL 63

  Fly   105 ---TPFHAVSPWQ-----------DEDTIKHLFSITRPKLIFC-DGKCFQRLSIIARILKSHVYT 154
               ..|:||| ||           .:...:......:.||:.. :|........:
pombe    64 EFVVAFYAVS-WQRAICGPLNSNYKQSEFEFYIDDLKSKLVIVPEGSVAANTPAV---------- 117

  Fly   155 LKDHRLGMPRVEDLLEPTTAELYYVPETLL----------------LG---GDHTVAILCTSGTT 200
                     |....|....|||.:.|::.|                ||   .|..:.:|.|||||
pombe   118 ---------RAAKKLSVAVAELAWCPKSRLVRIVHFEGAKINAPQPLGLPQPDDVMLVLHTSGTT 173

  Fly   201 GLPKAVCISN-SACLFDFGFVTG-----QD----VLLSFSTIDWSAGMFNMLFSCCHGSTRIITD 255
            |.||.|.::: :.|.......|.     :|    |:..|.......|:.:.|.|   |...::..
pombe   174 GRPKVVPLTHKNLCRSIHNITTSYRLDPRDTSYVVMPLFHVHGLLCGLLSTLAS---GGCAVVPP 235

  Fly   256 RPYTPEYMIQLVEKYKVTLLTVVPQQVASLLKTPTLNKQRLASIRFVSVGGGSC---YVANLLKL 317
            :.....:..:.:: |..|..|.||.....||:||.  .:.|..|||:.    ||   ....:|..
pombe   236 KFSAHSFWKEFIQ-YGATWYTAVPTIHQILLRTPP--PKPLPRIRFIR----SCSSPLAPPVLSK 293

  Fly   318 QEFLITGQISYGYALTECGGVAANMG----VAKPSSVGRIVP-GVRVKILDEAGRSLGHGETGEI 377
            .|......:...||:||.........    |.||.|||:  | ||.:||||:.|..:..|:.|||
pombe   294 LEATFRAPVLEAYAMTEASHQMTTNPLPPLVHKPHSVGK--PFGVELKILDQKGNEMPQGKEGEI 356

  Fly   378 LVHNGKVWNGYYANPNESKRMQDYQGWFHTGDMGYFDNENYLHIVERKEDLLRFHGAQYSPQEIE 442
            .|....|..||..||..:|.......:|.|||.|..|.:.|:.|..|.::|:...|.:.||.||:
pombe   357 CVRGINVTKGYLNNPAANKSSFTKDRFFRTGDEGKLDKDGYVFITGRIKELVNRGGEKISPAEID 421

  Fly   443 QVIAELPDVIEACVFGLWNEVDGDPAAAAVVKIPGSRLTEMDIVEYVAKRLV---VDHKQLHCGV 504
            .|:.:.|||.||..|.:.:|..|....||:..:.|..:|...:.:|:.:::.   :..|     .
pombe   422 AVLMQHPDVSEAVCFAVPDEKYGQDIQAAINPVAGKTVTPKQLHDYLEQKVAAFKIPKK-----F 481

  Fly   505 FFLPELPKTGSGKVLRQQARD 525
            :|...:|||.:|||.|:...|
pombe   482 YFTDRIPKTATGKVQRRLVCD 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11453	NP_650832.1	CaiC	18..530	CDD:223395	139/541 (26%)
CG11453	NP_650832.1	Firefly_Luc_like	46..519	CDD:213279	136/533 (26%)
SPCC1827.03c	NP_001342732.1	FACL_fum10p_like	160..502	CDD:213292	104/358 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X778
TreeFam	0	0.000	Not matched by this tool.
	3	2.810