DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11453 and Acsm3

DIOPT Version :9

Sequence 1:	NP_650832.1	Gene:	CG11453 / 42355	FlyBaseID:	FBgn0038734	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	XP_006230168.1	Gene:	Acsm3 / 24763	RGDID:	62086	Length:	581	Species:	Rattus norvegicus

Alignment Length:	513	Identity:	127/513 - (24%)
Similarity:	213/513 - (41%)	Gaps:	94/513 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 KAMGLKQDDVVGIVGTNTTYLMPVV-------LGCLLNGTPFHAVSPWQDEDTIKHLFSITRPKL 130
            :|..|::.|.|.::       :|.:       :.||..||.....:....:..|.:....::.|.
  Rat   107 EACSLQRGDRVMVI-------LPKIPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKSKC 164

  Fly   131 IFCDGKCFQRLSIIA---RILKSHVYTLKDHRLGMPRVEDLLEPTTAELYYVPETLLLGGDHT-- 190
            |..|......:.|:|   ..|.|.:...:..|.|...::::::       |..::      ||
  Rat   165 IITDDTLAPAVDIVAAKCENLHSKLIVSQHSREGWGNLKEMMK-------YASDS------HTCV 216

  Fly   191 -------VAILCTSGTTGLPKAVCISNSACLFDFGF-VTGQ--------DVLLSFSTIDWSAGMF 239
                   :||..||||||.||.:..::|:  |..|. |.|:        ||:.:.|...|:...:
  Rat   217 DTKHNELMAIYFTSGTTGPPKMIGHTHSS--FGLGLSVNGRFWLDLIASDVMWNTSDTGWAKSAW 279

  Fly   240 NMLFS------CCHGSTRIITDRPYTPEY----MIQLVEKYKVTLLTVVPQQVASLLKTPTLNKQ 294
            :.:||      |....        |.|.:    ::|.:.|:.:|:....|.....|::.......
  Rat   280 SSVFSPWTQGACVFAH--------YLPRFDSTSILQTLSKFPITVFCSAPTAYRMLIQNDITRSY 336

  Fly   295 RLASIRFVSVGGGSCYVANLLKLQEFLITGQISYGYALTE----CGGVAANMGVAKPSSVGRIVP 355
            :..|::. .|..|......:::..:......|..||..||    ||.. ..|.: ||.|:|:..|
  Rat   337 KFNSLKH-CVSAGEPINPEVMEQWKKKTGLDIYEGYGQTETVLICGNF-KGMKI-KPGSMGKPSP 398

  Fly   356 GVRVKILDEAGRSLGHGETGEILV-----HNGKVWNGYYANPNESKRMQDYQGWFH-TGDMGYFD 414
            ...|:||||.|..|..|:.|:|.|     ....::..|..||  ||.....:|.|: |||.||.|
  Rat   399 AFNVEILDENGTILPPGQEGDIAVQVLPDRPFGLFTHYVDNP--SKTASTLRGNFYITGDRGYMD 461

  Fly   415 NENYLHIVERKEDLLRFHGAQYSPQEIEQVIAELPDVIEACVFGLWNEVDGDPAAAAVVKIPGSR 479
            .:.|...|.|.:|::...|.:..|.|:|..:.|.|.:.|:.|....:.:.|:...|.:|..|..:
  Rat   462 EDGYFWFVARSDDVILSSGYRIGPFEVESALIEHPSIAESAVVSSPDPIRGEVVKAFIVLNPDYK 526

  Fly   480 LTEM-----DIVEYVAKRLVVDHKQLHCGVFFLPELPKTGSGKVLRQQARDQALGKKW 532
            |.:.     :|.|:| |:....:|... .:.|:.|||||.||||.|.:.|    .|:|
  Rat   527 LHDQEQLKKEIQEHV-KKTTAPYKYPR-KIEFIEELPKTVSGKVKRNELR----RKEW 578

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11453	NP_650832.1	CaiC	18..530	CDD:223395	125/509 (25%)
CG11453	NP_650832.1	Firefly_Luc_like	46..519	CDD:213279	122/498 (24%)
Acsm3	XP_006230168.1	Acs	45..575	CDD:223442	125/508 (25%)
Acsm3	XP_006230168.1	AFD_class_I	48..578	CDD:302604	126/511 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010