DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG11453 and Acsm2

DIOPT Version :9

Sequence 1:NP_650832.1 Gene:CG11453 / 42355 FlyBaseID:FBgn0038734 Length:539 Species:Drosophila melanogaster
Sequence 2:NP_653349.1 Gene:Acsm2 / 246263 RGDID:708383 Length:572 Species:Rattus norvegicus


Alignment Length:523 Identity:128/523 - (24%)
Similarity:219/523 - (41%) Gaps:69/523 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly    58 NGEAITFAIRIAQQLK---------AMGLKQDDVVGIVGTNTTYLMPVVLGCLLNGTPFHAVSPW 113
            :||.:.:..|...::.         |.||::.|.|.:|.........|.|||:.:|..|...:..
  Rat    75 SGEELKWNFRELSEISKQTANVLTGACGLQRGDRVAVVLPRVPEWWLVTLGCMRSGLVFMPGTTQ 139

  Fly   114 QDEDTIKHLFSITRPKLIFCDGKCFQRLSIIA---RILKSHVYTLKDHRLGMPRVEDLLEPTTAE 175
            .....|.:....::.:.|....:..|.:..:|   ..||..:...:.:|.|....:.||: ..:.
  Rat   140 MKSTDILYRLQSSKARAIVAGDEVVQEVDAVAPDCSFLKIKLLVSEKNREGWLNFKALLK-DASP 203

  Fly   176 LYYVPETLLLGGDHTVAILCTSGTTGLPKAV----CISNSACLFDFGFVTG---QDVLLSFSTID 233
            ::...||:   ...:.||..||||:|.||..    |........|.|: ||   .|.:.:.|...
  Rat   204 IHQCVETV---SQESAAIYFTSGTSGPPKMAEHSHCSLGLKAKMDAGW-TGLGPSDTMWTISDTG 264

  Fly   234 WSAGMFNMLFSCCH----GSTRIITDRP-YTPEYMIQLVEKYKVTLLTVVPQQVASLLKTPTLNK 293
            |   :.|:|.|...    |:...:...| :.|:.:::::..|.:..|...|.....||      :
  Rat   265 W---ILNILGSFLEPWVLGTCIFVHLLPKFDPQTVLKVLSSYPINTLLGAPLIYRMLL------Q 320

  Fly   294 QRLASIRFVSVGGGSCYVANLLKLQEFLITGQISYG------YALTECG---GVAANMGVAKPSS 349
            |.|:|.:|..:  .||:......|.|.|.:.:...|      |..||.|   .|:..|.| ||..
  Rat   321 QDLSSYKFPHL--HSCFSGGETLLPETLESWKAKTGLEIREIYGQTETGITCRVSRTMKV-KPGY 382

  Fly   350 VGRIVPGVRVKILDEAGRSLGHGETGEILVHNGKV-----WNGYYANPNESKRMQDYQGWFHTGD 409
            :|..:....|:::||.|..|..|:.|::.:....:     ::||..||.:::.......|. .||
  Rat   383 LGTAIVPYDVQVIDEQGNVLPPGKEGDMALRVKPIRPIGMFSGYVDNPKKTQANIRGDFWL-LGD 446

  Fly   410 MGYFDNENYLHIVERKEDLLRFHGAQYSPQEIEQVIAELPDVIEACVFGLWNEVDGDPAAAAVVK 474
            .|..|.|.|.|.:.|.:|::...|.:..|.|:|..:.|.|.|:|..|....:.:..:...|.||.
  Rat   447 RGIKDTEGYFHFMGRTDDIINSSGYRIGPSEVENALMEHPAVVETAVISSPDPIRREVVKAFVVL 511

  Fly   475 IP------GSRLTEMDIVEYVAKRLVVDHKQLHCGVFFLPELPKTGSGKVLRQQARDQALGKKWA 533
            .|      ..:||:: :.|:| |.:...:|... .|.|:.:||||.:||:.|.:.|    .|:|.
  Rat   512 APEFLSHDQDQLTKV-LQEHV-KSVTAPYKYPR-KVEFVLDLPKTITGKIERAKLR----AKEWK 569

  Fly   534 DHG 536
            ..|
  Rat   570 TSG 572

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG11453NP_650832.1 CaiC 18..530 CDD:223395 125/515 (24%)
Firefly_Luc_like 46..519 CDD:213279 123/504 (24%)
Acsm2NP_653349.1 AFD_class_I 40..568 CDD:302604 126/517 (24%)
Acs 40..565 CDD:223442 125/514 (24%)
Coenzyme A binding. /evidence=ECO:0000250 469..471 0/1 (0%)
Coenzyme A binding. /evidence=ECO:0000250 540..542 0/1 (0%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D683933at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.010

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