DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11453 and Acsm4

DIOPT Version :9

Sequence 1:	NP_650832.1	Gene:	CG11453 / 42355	FlyBaseID:	FBgn0038734	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_848501.1	Gene:	Acsm4 / 233801	MGIID:	2681844	Length:	580	Species:	Mus musculus

Alignment Length:	498	Identity:	125/498 - (25%)
Similarity:	204/498 - (40%)	Gaps:	65/498 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 KAMGLKQDDVVGIVGTNTTYLMPVVLGCLLNGTPFHAVSPWQDEDTIKHLFSITRPKLIF----C 133
            |..||::.|.|.::.........:.:.|:..|..|           :.....:||..:::    .
Mouse   107 KPCGLQRGDRVAVILPRIPEWWLINVACMRTGLVF-----------MPGTIQLTRKDILYRLQAS 160

  Fly   134 DGKCFQRL--------SIIARI--LKSHVYTLKDHRLGMPRVEDLLEPTTAELYYVPETLLLGGD 188
            ..||....        ||::..  ||:.:.....|..|....::||: :.:|.:...||   |..
Mouse   161 KAKCIVASEEVAPAVDSIVSECPSLKTKLLVSPHHWDGWLNFQELLQ-SASEEHNCVET---GSQ 221

  Fly   189 HTVAILCTSGTTGLPKAVCISNSACLFDFGF---------VTGQDVLLSFSTIDWSAGMFNMLFS 244
            ..:||..||||||.||..  .:|......|:         :|..|::.:.|...|.......:||
Mouse   222 EPMAIYFTSGTTGSPKMA--QHSQGSLGIGYTLCGRYWLDLTSSDIMWNMSDTGWIKAAIGSVFS 284

  Fly   245 CCHGSTRIITDR--PYTPEYMIQLVEKYKVTLLTVVPQQVASLLKTPTLNKQRLASIRFVSVGGG 307
            .......:...|  .:..:..:..:..|.:|.|...| .|..:|....|.:.:...:|....||.
Mouse   285 TWLRGACVFVHRMAQFDTDIFLDTLTTYPITTLCSAP-TVYRMLVQKDLKRYQFKRLRHCLTGGE 348

  Fly   308 --SCYVANLLKLQEFLITG-QISYGYALTECGGVAAN-MGVA-KPSSVGRIVPGVRVKILDEAGR 367
              :..|....|:|    || ::..||..||.|.:.|| .|.| ||.|:|:.|....|:|:||.|.
Mouse   349 PLNPEVLEQWKMQ----TGLELYEGYGQTEVGIICANRKGEAIKPGSMGKGVVPYDVQIIDENGN 409

  Fly   368 SLGHGETGEILVHNGK-----VWNGYYANPNESKRMQDYQGWFHTGDMGYFDNENYLHIVERKED 427
            .|..|:.|||.:....     .::.|..|| |.......:.::.|||.|..|::.|...|.|.:|
Mouse   410 ILPSGKEGEIALRLKSDRPFCFFSEYVDNP-EKTDATIRRNFYVTGDRGVMDDDGYFWFVGRADD 473

  Fly   428 LLRFHGAQYSPQEIEQVIAELPDVIEACVFGLWNEVDGDPAAAAVV-----KIPGSRLTEMDIVE 487
            ::...|.:..|.|:|..:.|.|.|:|:.|....:.:.|:...|.:|     |.........::.:
Mouse   474 VIISSGYRIGPFEVESALIEHPAVVESAVVSSPDPIRGEVVKAFIVLAAPYKCSNREKLTAELQD 538

  Fly   488 YVAKRLVVDHKQLHCGVFFLPELPKTGSGKVLRQQARDQALGK 530
            :| |.....:|... .|.|:.|||||.:||:.|...|||..|:
Mouse   539 HV-KNSTAPYKYPR-KVEFVQELPKTITGKIKRNVLRDQEWGR 579

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11453	NP_650832.1	CaiC	18..530	CDD:223395	124/496 (25%)
CG11453	NP_650832.1	Firefly_Luc_like	46..519	CDD:213279	120/485 (25%)
Acsm4	NP_848501.1	MACS_euk	48..577	CDD:213294	124/494 (25%)
Acsm4	NP_848501.1	Acs	49..576	CDD:223442	123/493 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920