Protein Alignment CG11453 and ACSM1

DIOPT Version :9

• Sequence 1: NP_650832.1
• Gene: CG11453 / 42355
• FlyBaseID: FBgn0038734
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_001305819.1
• Gene: ACSM1 / 116285
• HGNCID: 18049
• Length: 577
• Species: Homo sapiens
• Alignment Length: 561
• Identity: 133/561 - (23%)
• Similarity: 230/561 - (40%)
• Gaps: 100/561 - (17%)

  Fly    17 GPRPASFFDADCSIGKILFAFMRNHPNSICQISDTEGTALTNGEAITFAIRIAQQLKAMGLKQDD 81
            ||.|| |:..:....::.::|.        ::.|     ||...|..|.       :..||:|.|
Human    69 GPNPA-FWWVNGQGDEVKWSFR--------EMGD-----LTRRVANVFT-------QTCGLQQGD 112

  Fly    82 VVGIVGTNTTYLMPVVLGCLLNGTPFHAVSPWQDEDTIKHLFSITRPK-LIFCDGKCFQRLSIIA 145
            .:.::.........|.:||:..|..|...:.......|.:...:::.| ::..|....:..||.:
Human   113 HLALMLPRVPEWWLVAVGCMRTGIIFIPATILLKAKDILYRLQLSKAKGIVTIDALASEVDSIAS 177

  Fly   146 RI--LKSHVYTLKDHRLGMPRVEDLLEPTTAELYYVPETLLLGGDHTVAILCTSGTTGLPKAVCI 208
            :.  ||:.:......|.|......|::..:.|...|....|    ..:.|..||||||.||....
Human   178 QCPSLKTKLLVSDHSREGWLDFRSLVKSASPEHTCVKSKTL----DPMVIFFTSGTTGFPKMAKH 238

  Fly   209 SN----------------------SACLFDFGFVTGQDVLLSFSTID-WSAGMFNMLFSCCHGST 250
            |:                      |.||.|.|::    |...::.:: |:||....:.......|
Human   239 SHGLALQPSFPGSRKLRSLKTSDVSWCLSDSGWI----VATIWTLVEPWTAGCTVFIHHLPQFDT 299

  Fly   251 RIITDRPYTPEYMIQLVEKYKVTLLTVVPQQVASLLKTPTLNKQRLASIRFVSVGGGSCYVAN-- 313
            ::|          ||.:.||.:.....|......:|      :|...||||.::  ..||...
Human   300 KVI----------IQTLLKYPINHFWGVSSIYRMIL------QQDFTSIRFPAL--EHCYTGGEV 346

  Fly   314 -LLKLQE--FLITGQISY-GYALTECGGVAAN-MGV-AKPSSVGRIVPGVRVKILDEAGRSLGHG 372
             |.|.||  ...||.:.| .|..:|.|.:.|. .|: .||..:|:..|...|:::|:.|..|...
Human   347 VLPKDQEEWKRRTGLLLYENYGQSETGLICATYWGMKIKPGFMGKATPPYDVQVIDDKGSILPPN 411

  Fly   373 ETGEI-----LVHNGKVWNGYYANPNESKRMQ--DYQGWFHTGDMGYFDNENYLHIVERKEDLLR 430
            ..|.|     .|....::..|..:|.::.:::  |:   ::|||.|..|.|.|:..:.|.:|::.
Human   412 TEGNIGIRIKPVRPVSLFMCYEGDPEKTAKVECGDF---YNTGDRGKMDEEGYICFLGRSDDIIN 473

  Fly   431 FHGAQYSPQEIEQVIAELPDVIEACVFGLWNEVDGDPAAAAVVKIP------GSRLTEMDIVEYV 489
            ..|.:..|.|:|..:.|.|.|.|:.|.|..:.:.|:...|.:|..|      ..:||: ::.::|
Human   474 ASGYRIGPAEVESALVEHPAVAESAVVGSPDPIRGEVVKAFIVLTPQFLSHDKDQLTK-ELQQHV 537

  Fly   490 AKRLVVDHKQLHCGVFFLPELPKTGSGKVLRQQARDQALGK 530
             |.:...:|... .|.|:.|||||.:||:.|::.|.:..|:
Human   538 -KSVTAPYKYPR-KVEFVSELPKTITGKIERKELRKKETGQ 576

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11453	NP_650832.1	CaiC	18..530	CDD:223395	131/558 (23%)
		Firefly_Luc_like	46..519	CDD:213279	124/519 (24%)
ACSM1	NP_001305819.1	MACS_euk	45..574	CDD:341251	132/557 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920