DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11407 and 4CL2

DIOPT Version :9

Sequence 1:	NP_650831.1	Gene:	CG11407 / 42354	FlyBaseID:	FBgn0038733	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	NP_188761.1	Gene:	4CL2 / 821678	AraportID:	AT3G21240	Length:	556	Species:	Arabidopsis thaliana

Alignment Length:	545	Identity:	134/545 - (24%)
Similarity:	252/545 - (46%)	Gaps:	35/545 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 DRKIWSGDQL------EYYFDPHLSIGEIIFNEMRRHPQLIAQISATENTILTRAELQANAMHIA 70
            |:|..|.|.:      :.|...||.:.:.||..:.........|:.....:.|.|::...:..:|
plant    13 DQKQCSNDVIFRSRLPDIYIPNHLPLHDYIFENISEFAAKPCLINGPTGEVYTYADVHVTSRKLA 77

  Fly    71 SYMRSLGLLQMDIVGIIARNTTHISAVAYACFFNGIAFHSLNISYEQSTIEKLFSITRPNIIFCD 135
            :.:.:||:.|.|:|.|:..|:..:.....|..|.|....|.|..:..:.|.|....:...:|...
plant    78 AGLHNLGVKQHDVVMILLPNSPEVVLTFLAASFIGAITTSANPFFTPAEISKQAKASAAKLIVTQ 142

  Fly   136 GDEFEKVRSATAQLD-VKIITMRNH--PSGSIRIDQVLSTPIEKNFQPVRLEQGNDQTLAILCSS 197
            ....:|:::  .|.| |.|:|..:.  |...:|..: |:...|.....:..:...:..:|:..||
plant   143 SRYVDKIKN--LQNDGVLIVTTDSDAIPENCLRFSE-LTQSEEPRVDSIPEKISPEDVVALPFSS 204

  Fly   198 GTTGIPKAVTITNSRQILNSSHSLTTNDVQYSHSTLDWITGLLT-----TVTSGVFSTKRIIADN 257
            ||||:||.|.:|:...:.:.:..:...:.....:..|.|..:|.     .:.|.:..:.|:.|..
plant   205 GTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFNRDDVILCVLPMFHIYALNSIMLCSLRVGATI 269

  Fly   258 IFDPEFFMRLVEEH----QITWIIQAPAHMAMMVNSPSFTTSDLSSLRYYLFGGSRASVETQHRI 318
            :..|:|.:.|:.|.    ::|..:..|..:..:..||.....||||:|....|.:....|.:..|
plant   270 LIMPKFEITLLLEQIQRCKVTVAMVVPPIVLAIAKSPETEKYDLSSVRMVKSGAAPLGKELEDAI 334

  Fly   319 RSRLSKDCLHFAYGFTELGSMAALNLHFDEKP-----NSVGRLVAGLKLKVI-CEKGESLGPDEV 377
            .::.....|...||.||.|.:.|::|.|.::|     .:.|.:|...::|:: .:.|:||..::.
plant   335 SAKFPNAKLGQGYGMTEAGPVLAMSLGFAKEPFPVKSGACGTVVRNAEMKILDPDTGDSLPRNKP 399

  Fly   378 GELCLWNGQYWAGYYGNPEETHKMRDHHNWFHTGDLGYVDDDGFIYIVERKKDMLKFQNIMYYPN 442
            ||:|:...|...||..:|..|....|...|.||||:|::|||..::||:|.|:::|::.....|.
plant   400 GEICIRGNQIMKGYLNDPLATASTIDKDGWLHTGDVGFIDDDDELFIVDRLKELIKYKGFQVAPA 464

  Fly   443 EIESVISKMPDVVEVCVFGVWNEINGDEATAAVVKKRGSALTAQDIVDYVETHIDAKYKQLNGGA 507
            |:||::...|::.:|.|..:..|..|:...|.||:.:.|.::..:|..:|...: ..||::| ..
plant   465 ELESLLIGHPEINDVAVVAMKEEDAGEVPVAFVVRSKDSNISEDEIKQFVSKQV-VFYKRIN-KV 527

  Fly   508 IIVEDLVRSPNGK------TNRMAN 526
            ...:.:.::|:||      ..|:||
plant   528 FFTDSIPKAPSGKILRKDLRARLAN 552

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11407	NP_650831.1	CaiC	26..523	CDD:223395	126/520 (24%)
CG11407	NP_650831.1	Firefly_Luc_like	47..522	CDD:213279	122/498 (24%)
4CL2	NP_188761.1	PLN02246	14..553	CDD:215137	133/544 (24%)
4CL2	NP_188761.1	4CL	32..546	CDD:213272	126/518 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24096
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920