DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11407 and Acsf2

DIOPT Version :9

Sequence 1:	NP_650831.1	Gene:	CG11407 / 42354	FlyBaseID:	FBgn0038733	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	NP_001030123.1	Gene:	Acsf2 / 619561	RGDID:	1562656	Length:	615	Species:	Rattus norvegicus

Alignment Length:	548	Identity:	136/548 - (24%)
Similarity:	245/548 - (44%)	Gaps:	51/548 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 LEYYFDPHL---SIGEIIFNEMRRHPQLIAQISATENTILTRAELQANAMHIASYMRSLGLLQMD 82
            ::.:.|.||   ::||.:....:|.|...|.:...||..|..|:|:......||.:.|:||.:.|
  Rat    61 IQGHTDSHLVNKTVGECLDATAQRFPNREALVIIHENIRLNFAQLKEEVDRAASGLLSIGLRKGD 125

  Fly    83 IVGIIARNTTHISAVAYACFFNGIAFHSLNISYEQSTIEKLF------SITRP---------NII 132
            .:|:...|:.....:..|....||...|:|.:|:.|.:|.:.      .|..|         ||:
  Rat   126 RLGMWGPNSYAWVLIQLATAQAGIILVSVNPAYQASELEYVLRKVGCKGIVFPKQFKTQQYYNIL 190

  Fly   133 FCDGDEFEKVRSATAQLD-----VKIITMRNHPSGSIRIDQVLST-PIEKNFQPVRLEQG---ND 188
            .....|.||.:....:.:     ..:|::.....|::.:|:|::. ..|:|...:|..||   ..
  Rat   191 KQVCPELEKAQPGALKSERLPDLTTVISVDAPLPGTLLLDEVVAAGGKEQNLAQLRYHQGFLSCY 255

  Fly   189 QTLAILCSSGTTGIPKAVTITNSRQILNSSHSL---------TTNDVQY-----SHSTLDWITGL 239
            ..:.|..:|||||.||..|::: ..|:|:|:.:         |..:::.     .:..|..:.|.
  Rat   256 DPINIQFTSGTTGNPKGATLSH-HNIVNNSNLIGQRLKMPAKTAEELRMVLPCPLYHCLGSVGGT 319

  Fly   240 LTTVTSGVFSTKRIIADNIFDPEFFMRLVEEHQITWIIQAPAHMAMMVNSPSFTTSDLSSLRYYL 304
            :.:|..|   ...:::...|:.:..:..:...:.|.:...|.....::|.|.|::.|.:::|..:
  Rat   320 MVSVVHG---ATLLLSSPSFNGKKALEAISREKGTLLYGTPTMFVDILNQPDFSSYDFTTIRGGV 381

  Fly   305 FGGSRASVETQHRIRSRLSKDCLHFAYGFTELGSMAALNLHFD---EKPNSVGRLVAGLKLKVI- 365
            ..||.|..|....|.|:::...|...||.||...:..:|...|   :|..||||::...:.:::
  Rat   382 IAGSLAPPELIRAIISKMNMKELVVVYGTTENSPVTFMNFPEDTLEQKAGSVGRIMPHTEAQIVN 446

  Fly   366 CEKGESLGPDEVGELCLWNGQYWAGYYGNPEETHKMRDHHNWFHTGDLGYVDDDGFIYIVERKKD 430
            .|.||....:..||||:.......||:|.|::|.:......|:.|||:..:|:.||..||.|.||
  Rat   447 METGELTKLNMPGELCIRGYCVMQGYWGEPQKTFETVGQDRWYRTGDIASMDEQGFCRIVGRSKD 511

  Fly   431 MLKFQNIMYYPNEIESVISKMPDVVEVCVFGVWNEINGDEATAAVVKKRGSALTAQDIVDYVETH 495
            |:.......||.|:|....|.|.|.|..|.||.::..|:|..|.:..|.|...|.::|..:.:..
  Rat   512 MIIRGGENIYPAELEDFFHKHPQVQEAQVVGVKDDRMGEEICACIRLKSGETTTEEEIKAFCKGK 576

  Fly   496 IDAKYKQLNGGAIIVEDLVRSPNGKTNR 523
            |  .:.::....:.||....:.:||..:
  Rat   577 I--SHFKIPRYIVFVEGYPLTVSGKIQK 602

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11407	NP_650831.1	CaiC	26..523	CDD:223395	136/541 (25%)
CG11407	NP_650831.1	Firefly_Luc_like	47..522	CDD:213279	129/516 (25%)
Acsf2	NP_001030123.1	PRK08315	57..615	CDD:236236	136/548 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810