DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11407 and acsl3a

DIOPT Version :9

Sequence 1:	NP_650831.1	Gene:	CG11407 / 42354	FlyBaseID:	FBgn0038733	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	NP_001038593.1	Gene:	acsl3a / 567157	ZFINID:	ZDB-GENE-050420-181	Length:	713	Species:	Danio rerio

Alignment Length:	576	Identity:	125/576 - (21%)
Similarity:	202/576 - (35%)	Gaps:	153/576 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 EIIFNEMR--RHPQLIAQISATENTILTRAELQANAMHIASYMRSLGLLQMDIVGIIARNTTHIS 95
            ::|..|.|  .:.|:..:::|                 ..|.:.:||...|..:.|.........
Zfish   119 KVILGEYRWMSYEQVFKEVNA-----------------FGSGLAALGQKPMKNIAIFCETRAEWI 166

  Fly    96 AVAYACFFNGIAFHSLNISYEQSTIEKLFSITRPNIIFCDGDEFE-KVRSATAQ---------LD 150
            ..|.|||.......:|..:.....|....:....:.|....|..| |::|...:         :|
Zfish   167 IAAQACFMYNFPLVTLYSTLGGPAIAHGLNEAEVSHIITSKDLLETKLKSIFIEVPRLCHVIVVD 231

  Fly   151 VKIITMRNHPSGSIRIDQVLSTPIEKNFQPVRLEQG-----NDQTLAILCSSGTTGIPKAVTITN 210
            .|:.|...:|.| |.|..:.|.. |...:|....:.     :.....|:.:||:||:||.|.|::
Zfish   232 DKLSTSSEYPRG-ISIHSMASVK-ELGARPENASKPKNPPCSSDVAVIMYTSGSTGVPKGVMISH 294

  Fly   211 SR---QILNSSH---SLTTNDVQYSHSTLDWITGL---LTTVTSGV---FSTKRIIADNIFD--- 260
            |.   .|...:|   .|..:|....:..|..:..|   :..:..|.   :|:.:.::|....
Zfish   295 SNIISGITGMTHRIPKLVEDDTYIGYLPLAHVLELSAEMVCLAHGCRIGYSSPQTLSDQSTKIKK 359

  Fly   261 -----------------PEFFMRL-------VEE---HQITWIIQA----PAHMAMMVNSPSFTT 294
                             ||...|:       ||:   .|.|..:.|    ...:||..::|  ..
Zfish   360 GSRGDISVLRPTLMAAVPEIMDRIYKNVMLRVEQMSGFQRTLFLLAYNYKMEQLAMGYSTP--LC 422

  Fly   295 SDL----------SSLRYYLFGGSRASVETQHRIRSRLSKDC----LHFAYGFTELGSMAALNLH 345
            ..|          ..||..|.||:..|..||     |....|    :...||.||......::..
Zfish   423 DKLVFRKVRALLGGRLRVLLSGGAPLSAATQ-----RFMNICFCCPVGQGYGLTETCGAGTISHL 482

  Fly   346 FDEKPNSVGR--LVAGLKLKVICEKG--ESLGPDEVGELCLWNGQYWAGYYGNPEETHKMRDH-- 404
            :|.....||.  :...|:||...|.|  .:..|...||:.:.......|||.|   |||..:.
Zfish   483 WDYSTGRVGAPLVCCELQLKDWIEGGYHSTDLPCPRGEILVGGPSITMGYYKN---THKTSEDFF 544

  Fly   405 -----HNWFHTGDLGYVDDDGFIYIVERKKDMLKFQNIMYYP-NEIESVISKMPDVVEVCVF--- 460
                 ..||.|||:|.:..||.:.|::||||::|.|...|.. .::|:.:...|.|..:|.:
Zfish   545 VDKKGQRWFCTGDIGEIHGDGCLKIIDRKKDLVKLQAGEYVSLGKVEAALKNCPLVDNICAYANS 609

  Fly   461 --------------------------GVWNEING----DEATAAVVKKRGSALTAQ 486
                                      |:|.|:..    :||...|:.:  :|||||
Zfish   610 DESYVIGFVVPNQKQLLALAERKRVRGLWEELCNNPVIEEAVLTVLTE--AALTAQ 663

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11407	NP_650831.1	CaiC	26..523	CDD:223395	125/576 (22%)
CG11407	NP_650831.1	Firefly_Luc_like	47..522	CDD:213279	121/560 (22%)
acsl3a	NP_001038593.1	PLN02387	77..710	CDD:215217	125/576 (22%)
acsl3a	NP_001038593.1	LC-FACS_euk	123..710	CDD:213293	124/572 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583077
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930