DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11407 and acsf3

DIOPT Version :9

Sequence 1:	NP_650831.1	Gene:	CG11407 / 42354	FlyBaseID:	FBgn0038733	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	XP_021329817.1	Gene:	acsf3 / 562292	ZFINID:	ZDB-GENE-121026-3	Length:	579	Species:	Danio rerio

Alignment Length:	536	Identity:	117/536 - (21%)
Similarity:	214/536 - (39%)	Gaps:	105/536 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 SATENTILTRAELQANAMHIASYMR-SLGLLQMDIVGIIARNTTHISAVAYACFFNGIAFHSLNI 113
            |.|.:::...:::.|.  ||...:. ..|.||...:..:..|....:...:|.:..|.....|..
Zfish    74 SHTYHSLYKNSKILAG--HITKALTCQSGDLQGKRISFLCANDASYTVAQWASWMCGGIAVPLYR 136

  Fly   114 SYEQSTIEKLFSITRPNIIFCDGDEFEKVRSATAQ-LDVKIITMRNHPSGSIRIDQVLSTPIEKN 177
            .:..|.:|.:.|.::.:::.. |..|.......|| |.:..:.:   |:.|.:.:...:.|.:
Zfish   137 KHPLSELEYVISDSQSSLLVA-GQSFVDTLEPLAQKLGLPCLKL---PATSSQFEDTQTLPED-- 195

  Fly   178 FQPVRLEQGNDQTLAILCSSGTTGIPKAVTITNSR-----QILNSSHSLTTNDVQYSHSTLDWIT 237
                .:....::...::.:|||||.||.|..|:|.     |.|.|..:...:||......|..:.
Zfish   196 ----MISDWAERPAMLIYTSGTTGRPKGVLHTHSSLQAMVQGLVSEWAWHKDDVILHTLPLHHVH 256

  Fly   238 GLL-----------TTVTSGVFSTKRIIAD---------NIF--DPEFFMRLVE---EH----QI 273
            |::           |.:....||.:::...         |:|  .|..:.:|:|   :|    |:
Zfish   257 GIVNKLMCPLWVGATCIMLPDFSAQKVWEQLICSKSPMVNVFMAVPTIYSKLIEYYDQHFTQPQV 321

  Fly   274 TWIIQA--PAHMAMMVNSPSFTTSDLSSLRYYLFGGSRASVE---------TQHRIRSRLSKDCL 327
            ...|:|  ...:.:||:                  ||.|..:         |.|.:..|
Zfish   322 QDFIRAVCKERIRLMVS------------------GSAALPQPVLERWAEITDHVLLER------ 362

  Fly   328 HFAYGFTELGSMAALNLHFDEK-PNSVGRLVAGLKLK------VICEKGESLGPD-------EVG 378
               ||.||:| ||..|.:...: |.:||..:.|::::      ::..:|.|.|..       :.|
Zfish   363 ---YGMTEIG-MALSNSYKGPRVPGAVGVPLPGVEVRIMMNSSIVIAEGTSKGTQVKAGLEGKEG 423

  Fly   379 ELCLWNGQYWAGYYGNPEETHKMRDHHNWFHTGDLGYVDDDGFIYIVERKK-DMLKFQNIMYYPN 442
            ||.:.....:..|:..|:||.:......||.|||.. :..||..:|:.|.. |::|.........
Zfish   424 ELLVRGSSVFQKYWNKPQETEESFTEDRWFKTGDTA-LYRDGVYWIMGRTSVDIIKSGGYKISAL 487

  Fly   443 EIESVISKMPDVVEVCVFGVWNEINGDEATAAVVKKRGSALTAQDIVDYVETHIDAKYKQLNGGA 507
            ::|..:...||:.:|.|.|..:...|.:.||.|..::|..:...|:..:...|: |.| .:..|.
Zfish   488 DVERHLLAHPDITDVAVIGAPDATWGQKVTAVVQMRKGKTMILSDLKAWAREHM-ASY-SIPTGL 550

  Fly   508 IIVEDLVRSPNGKTNR 523
            |:|||:.|:..||.|:
Zfish   551 ILVEDMPRNQMGKVNK 566

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11407	NP_650831.1	CaiC	26..523	CDD:223395	116/534 (22%)
CG11407	NP_650831.1	Firefly_Luc_like	47..522	CDD:213279	116/533 (22%)
acsf3	XP_021329817.1	MCS	64..566	CDD:213307	116/534 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900