DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11407 and CG18586

DIOPT Version :9

Sequence 1:	NP_650831.1	Gene:	CG11407 / 42354	FlyBaseID:	FBgn0038733	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	NP_647993.2	Gene:	CG18586 / 38659	FlyBaseID:	FBgn0035642	Length:	545	Species:	Drosophila melanogaster

Alignment Length:	524	Identity:	305/524 - (58%)
Similarity:	406/524 - (77%)	Gaps:	0/524 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 YDADRKIWSGDQLEYYFDPHLSIGEIIFNEMRRHPQLIAQISATENTILTRAELQANAMHIASYM 73
            ||...|||||.:....|.|:||||||||.:|..:|:||||||.||:.:|||.:|..|||.:||||
  Fly    17 YDDKLKIWSGREAPSLFSPNLSIGEIIFGDMVNNPKLIAQISITEDIVLTREDLHMNAMRVASYM 81

  Fly    74 RSLGLLQMDIVGIIARNTTHISAVAYACFFNGIAFHSLNISYEQSTIEKLFSITRPNIIFCDGDE 138
            |::||.|.||||::.|:|||.|||||||||||...|:|:.:||::.|.|||.||:|.:|||||||
  Fly    82 RNMGLGQTDIVGVMGRHTTHQSAVAYACFFNGTPLHALHNAYEEACIAKLFGITKPRLIFCDGDE 146

  Fly   139 FEKVRSATAQLDVKIITMRNHPSGSIRIDQVLSTPIEKNFQPVRLEQGNDQTLAILCSSGTTGIP 203
            :|||:|||..|.|.|:||||||.||:||..||:||:.:||||:||:.|.|.|||||.||||:|.|
  Fly   147 YEKVKSATKDLQVTIVTMRNHPRGSVRIQDVLTTPVMQNFQPLRLKDGIDHTLAILSSSGTSGFP 211

  Fly   204 KAVTITNSRQILNSSHSLTTNDVQYSHSTLDWITGLLTTVTSGVFSTKRIIADNIFDPEFFMRLV 268
            |||||:||.:|:....::..:::||:.|||||.:||...:|||||||..||||..|||..|.|.:
  Fly   212 KAVTISNSHKIIVDYMAINNSNIQYTSSTLDWCSGLSMAITSGVFSTTSIIADCDFDPGLFCRAI 276

  Fly   269 EEHQITWIIQAPAHMAMMVNSPSFTTSDLSSLRYYLFGGSRASVETQHRIRSRLSKDCLHFAYGF 333
            .:::|:.::.:.:::|:..|.|.|.::|||||.|.:||||..|:|.|.::|||||.|||:|.||.
  Fly   277 GKYRISMVLLSSSYLAIFANCPEFESADLSSLNYVIFGGSSCSLEVQRKVRSRLSHDCLNFCYGL 341

  Fly   334 TELGSMAALNLHFDEKPNSVGRLVAGLKLKVICEKGESLGPDEVGELCLWNGQYWAGYYGNPEET 398
            |||.|..::||:||||||||||.:.|:|:|||.|:||:..|:.|||:|..|.|.|||||.||:||
  Fly   342 TELNSAGSVNLNFDEKPNSVGRAIRGIKIKVIDEQGEAQEPNVVGEICFHNSQKWAGYYKNPDET 406

  Fly   399 HKMRDHHNWFHTGDLGYVDDDGFIYIVERKKDMLKFQNIMYYPNEIESVISKMPDVVEVCVFGVW 463
            .:::|..||.|||||||||.||::::::|.|||||:|||||||:|||:||::||:|:|.||||:|
  Fly   407 RQIQDSENWIHTGDLGYVDKDGYLFVIDRLKDMLKYQNIMYYPSEIENVIAEMPNVLEACVFGIW 471

  Fly   464 NEINGDEATAAVVKKRGSALTAQDIVDYVETHIDAKYKQLNGGAIIVEDLVRSPNGKTNRMANKA 528
            :.:|||||.|::|||.|:.|.|||:|:||...|.||:|||||||:||:.:|||.|.||||.|.|.
  Fly   472 DPVNGDEAAASLVKKPGTQLEAQDVVEYVRKRITAKFKQLNGGALIVDQIVRSGNRKTNRSAVKE 536

  Fly   529 FFLE 532
            .||:
  Fly   537 HFLK 540

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11407	NP_650831.1	CaiC	26..523	CDD:223395	291/496 (59%)
CG11407	NP_650831.1	Firefly_Luc_like	47..522	CDD:213279	277/474 (58%)
CG18586	NP_647993.2	CaiC	35..541	CDD:223395	297/506 (59%)
CG18586	NP_647993.2	AFD_class_I	55..530	CDD:302604	277/474 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471289
Domainoid	1	1.000	215	1.000	Domainoid score	I5876
eggNOG	1	0.900	-	-		E1_COG0318
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	290	1.000	Inparanoid score	I5187
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG26958
OrthoDB	1	1.010	-	-		D24284at7147
OrthoFinder	1	1.000	-	-		FOG0004528
OrthoInspector	1	1.000	-	-		mtm9651
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24096
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X778
	11	10.910