DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11407 and CG17999

DIOPT Version :9

Sequence 1:	NP_650831.1	Gene:	CG11407 / 42354	FlyBaseID:	FBgn0038733	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	NP_611517.1	Gene:	CG17999 / 37357	FlyBaseID:	FBgn0034552	Length:	545	Species:	Drosophila melanogaster

Alignment Length:	537	Identity:	159/537 - (29%)
Similarity:	274/537 - (51%)	Gaps:	33/537 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 YYDADRKIWSGDQLEYYFDPHLSIGEIIFNEMRRHPQLIAQISATENTILTRAELQANAMHIASY 72
            :|||..:.|.|.:.:.::.|.:::||:|...::.:...:.||..|....||.|:|...:..||..
  Fly     6 HYDAASRTWFGPRGKDFYGPEMTLGEVIMRVLQINADQVMQICDTTGQELTGAQLAQQSARIAQA 70

  Fly    73 MRSLGLLQMDIVGIIARNTTHISAVAYACFFNGIAFHSLNISYEQSTIEKLFSITRPNIIFCDGD 137
            .:.|||.:.|:|||.|.|:|::::|..|....||..:.|:..:.:.|::.::.||.|.:||||.:
  Fly    71 FKRLGLRRGDVVGISANNSTYLTSVIIAALLRGIPINPLHPEFTEETVKYMYDITEPKVIFCDVE 135

  Fly   138 EFEKVRSATAQLD--VKIITMRNHPSGSIRIDQVLS----------TPIEKNFQPVRLEQGNDQT 190
            .:..:::...:|.  .||..:.....|.:.|.::|:          .|..|        ...|.|
  Fly   136 NYHIIKTVNGKLQNPAKIYLVNGKLEGVLDISEMLNDEDSITAAAYVPCPK--------LHGDHT 192

  Fly   191 LAILCSSGTTGIPKAVTITNSRQILN--SSHSLTTNDVQYSHSTLDWITGLLTTVTSGVFSTKRI 253
            ..|:|||||||:||.||.::...:.|  :.::.|.:.|..|.|.|.||:|.:..:.|.:...:||
  Fly   193 AFIVCSSGTTGMPKGVTRSHRSLLCNCKNPNTYTRDSVLLSFSPLYWISGTIILLASLLNGCRRI 257

  Fly   254 IADNIFDPEFFMRLVEEHQITWIIQAPAHMAMMVNSPSFT---TSDLSSLRYYLFGGSRASVETQ 315
            |.:..:..|:.::||..|::|::..|...:|::....|..   .:.|.|:|..:..||:......
  Fly   258 ITNRPYSVEYLLQLVARHKVTFLFLASHQIALLSKHDSDVMELKAQLQSIRVLIGAGSKVCKAVC 322

  Fly   316 HRIRSRLSKDCLHFAYGFTELGSMAALNLHFDEKPNSVGRLVAGLKLKVICEKGESLGPDEVGEL 380
            .|:...:........||.:|:|   .|:.:........|:::..::|:|:.:....||.:|||.:
  Fly   323 RRMYELIGNQRFVVGYGLSEMG---GLSKNVGGPVGCEGKVMRNVELRVLDKLKMPLGINEVGII 384

  Fly   381 CLWNGQYWAGYYGNPEETHK-MRDHHNWFHTGDLGYVDDDGFIYIVERKKDMLKFQNIMYYPNEI 444
            .......|||||.|||.|.: :.....||.|||:||:|.:|::||..|..|:.||.|...||.:|
  Fly   385 YARLRFKWAGYYRNPEATRRALSSDGMWFRTGDIGYLDSEGYLYIQTRDTDVFKFNNFQIYPEQI 449

  Fly   445 ESVISKMPDVVEVCVFGVWNEINGDEATAAVVKKR---GSALTAQDIVDYVETHIDAKYKQLNGG 506
            |..|.::|.|.|.||||:.:.::.:....|||:.:   |..|||..|.:.||.|:...| .:.||
  Fly   450 EEFILRLPGVSEACVFGIPDAVSTNLTACAVVRTKSPEGERLTADHIRNIVEHHLSGAY-HIRGG 513

  Fly   507 AIIVEDLVRSPNGKTNR 523
            ...::.|.::||.|..|
  Fly   514 VYFIDSLPKTPNDKLQR 530

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11407	NP_650831.1	CaiC	26..523	CDD:223395	153/517 (30%)
CG11407	NP_650831.1	Firefly_Luc_like	47..522	CDD:213279	149/495 (30%)
CG17999	NP_611517.1	CaiC	25..545	CDD:223395	154/518 (30%)
CG17999	NP_611517.1	AFD_class_I	38..529	CDD:302604	149/502 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471333
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG26958
OrthoDB	1	1.010	-	-		D24284at7147
OrthoFinder	1	1.000	-	-		FOG0004528
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24096
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X778
	8	7.860