DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11407 and Acsm1

DIOPT Version :9

Sequence 1:	NP_650831.1	Gene:	CG11407 / 42354	FlyBaseID:	FBgn0038733	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	NP_001101972.2	Gene:	Acsm1 / 361638	RGDID:	1306813	Length:	577	Species:	Rattus norvegicus

Alignment Length:	579	Identity:	126/579 - (21%)
Similarity:	229/579 - (39%)	Gaps:	130/579 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 PASYYDADRKIWSGDQLEYYFDPHLSIGEIIFNEMRRHPQLIAQISATENTILTRAELQANAMHI 69
            ||.::..|:    ||::::           .|.|:|                    :|...|.::
  Rat    72 PALWWVNDQ----GDEIKW-----------SFRELR--------------------DLSRRAANV 101

  Fly    70 ASYMRSLGLLQMDIVGIIARNTTHISAVAYACFFNGIAF-------HSLNISYEQSTIEKLFSIT 127
              :.::.||...|.:.:|.........|...|...|:.|       .:.:|.|.....:....:|
  Rat   102 --FEQTCGLQHGDRLALILPRVPEWWLVTVGCIRTGVIFIPGTAQMKAKDILYRIQMSQAKAIVT 164

  Fly   128 RPNIIFCDGDEFEKVRSATAQLDVKIITMRNHPSGSIRIDQVLSTPIEKNFQPVRLEQGNDQT-- 190
            ..:::    .|.|.|.|....|..||:...::..|.:            ||:.:......|.|
  Rat   165 TDSLV----PEVESVASECPGLKTKIVVSDHNHEGWL------------NFRTLLRSASPDHTCV 213

  Fly   191 -------LAILCSSGTTGIPKAV----------TITNSRQILNSSHSLTTNDVQYSHSTLDWITG 238
                   :.|..:|||||.||..          ::.:.|:.|    .|.|:||.:..|...||..
  Rat   214 KSKMKDPMVIFFTSGTTGYPKMAKHNQGLAFRSSVPSCRKFL----KLKTSDVIWCMSDPGWILA 274

  Fly   239 ----LLTTVTSGVFSTKRIIADNI--FDPEFFMRLVEEHQITWIIQAPAHMAMMVNSPSFTTSDL 297
                ||...|:|.    .:...|:  |||:..:..:.::.||..:.|||...|::.      .::
  Rat   275 TVGCLLEPWTAGA----TVFVHNLPQFDPKVIVETLFKYPITQCLAAPAVYRMVLQ------KNI 329

  Fly   298 SSLRYYLF-----GGSRASVE--TQHRIRSRLSKDCLHFAYGFTELGSMAALNLHFDEKPNSVGR 355
            |:||:...     ||.....|  .|.:.|:.||   :|..||.:|.|...|:......|..|:|:
  Rat   330 SNLRFPTLEHCATGGESLLPEEYEQWKQRTGLS---IHEVYGQSETGITCAIFREMKVKRGSIGK 391

  Fly   356 LVAGLKLKVICEKGESLGPDEVGELCLWNG---------QYWAGYYGNPEETHKMRDHHNWFHTG 411
            .:....:::|.|||..|.|:..|.:    |         ..:.||..:||:|.:: :..:::::|
  Rat   392 AILPFDIQIIDEKGNILPPNTEGYI----GIRIKPTRPLGLFVGYENSPEKTSEV-ECGDFYNSG 451

  Fly   412 DLGYVDDDGFIYIVERKKDMLKFQNIMYYPNEIESVISKMPDVVEVCVFGVWNEINGDEATAAVV 476
            |...:|:||:|:.:.|..|::........|.|:|:.:.:.|.|.|..|....::..|:...|.:|
  Rat   452 DRATIDEDGYIWFLGRSDDVINASGYRIGPTEVENALVEHPAVSESAVVSSPDKDRGEVVKAFIV 516

  Fly   477 -KKRGSALTAQDIVDYVETH---IDAKYKQLNGGAIIVEDLVRSPNGKTNR--MANKAF 529
             .....:...:.::..::.|   :.|.||... ....|.:|.::..||..|  :.||.|
  Rat   517 LNPEFLSHDQEQLIKELQEHVKSVTAPYKYPR-KVEFVSELPKTITGKIKRKELRNKEF 574

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11407	NP_650831.1	CaiC	26..523	CDD:223395	117/548 (21%)
CG11407	NP_650831.1	Firefly_Luc_like	47..522	CDD:213279	114/526 (22%)
Acsm1	NP_001101972.2	AFD_class_I	46..573	CDD:302604	124/576 (22%)
Acsm1	NP_001101972.2	Acs	46..570	CDD:223442	123/573 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010