Protein Alignment CG11407 and ACSM2B

DIOPT Version :9

• Sequence 1: NP_650831.1
• Gene: CG11407 / 42354
• FlyBaseID: FBgn0038733
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_001098539.1
• Gene: ACSM2B / 348158
• HGNCID: 30931
• Length: 577
• Species: Homo sapiens
• Alignment Length: 514
• Identity: 119/514 - (23%)
• Similarity: 213/514 - (41%)
• Gaps: 57/514 - (11%)

  Fly    61 ELQANAMHIASYMR-SLGLLQMDIVGIIARNTTHISAVAYACFFNGIAFHSLNISYEQSTIEKLF 124
            ||..|:...|:.:. :.||.:.|.|.::.........|...|...|:.|....|..:.:.|....
Human    85 ELSENSQQAANILSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRL 149

  Fly   125 SITRPNIIFCDGD----EFEKVRSATAQLDVKIITMRNHPSGSIRIDQVLSTPIEKNFQPVRLEQ 185
            .:::...|.. ||    |.:.|.|....|.:|::.......|.:...::|:   |.:.....:|.
Human   150 QMSKAKAIVA-GDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLLN---EASTTHHCVET 210

  Fly   186 GNDQTLAILCSSGTTGIPKAVTITNSRQILNSS-----HSLTTNDVQYSHSTLDWITGLLTTV-- 243
            |:.:..||..:|||:|:||....:.|...|.:.     ..|..:|:.::.|...||..:|.::
Human   211 GSQEASAIYFTSGTSGLPKMAEHSYSSLGLKAKMDAGWTGLQASDIMWTISDTGWILNILGSLLE 275

  Fly   244 --TSGVFSTKRIIADNIFDPEFFMRLVEEHQITWIIQAPAHMAMMVNSPSFTTSDLSSLRY---- 302
              |.|..:...::..  |||...::.:..:.|..::.||....|::.      .||||.::
Human   276 SWTLGACTFVHLLPK--FDPLVILKTLSSYPIKSMMGAPIVYRMLLQ------QDLSSYKFPHLQ 332

  Fly   303 -YLFGGSRASVETQHRIRSRLSKDCLHFAYGFTELGSMAALNLHFDEKPNSVGRLVAGLKLKVIC 366
             .|.||.....||....|::...|...| ||.||.|....::.....||..:|...:...::||.
Human   333 NCLAGGESLLPETLENWRAQTGLDIREF-YGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQVID 396

  Fly   367 EKGESLGPDEVGELCLWNG---------QYWAGYYGNPEETHKMRDHHNWFHTGDLGYVDDDGFI 422
            :||..|.|...|::    |         ..::||..||::|........|. .||.|..|:||:.
Human   397 DKGNVLPPGTEGDI----GIRVKPIRPIGIFSGYVENPDKTAANIRGDFWL-LGDRGIKDEDGYF 456

  Fly   423 YIVERKKDMLKFQNIMYYPNEIESVISKMPDVVEVCVFGVWNEINGDEATAAVVKKRGSALTAQD 487
            ..:.|..|::........|:|:|:.:.|.|.|||..|....:.:.|:...|.|:  ..|...:.|
Human   457 QFMGRADDIINSSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVI--LASQFLSHD 519

  Fly   488 ---IVDYVETH---IDAKYKQLNGGAIIVEDLVRSPNGKTNR--MANKAFFLEAKSSAK 538
               :...::.|   :.|.||.......:: :|.::..||..|  :.:|.:.:..|:.|:
Human   520 PEQLTKELQQHVKSVTAPYKYPRKIEFVL-NLPKTVTGKIQRTKLRDKEWKMSGKARAQ 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11407	NP_650831.1	CaiC	26..523	CDD:223395	115/495 (23%)
		Firefly_Luc_like	47..522	CDD:213279	115/494 (23%)
ACSM2B	NP_001098539.1	AFD_class_I	40..568	CDD:388389	117/503 (23%)
		Coenzyme A binding. /evidence=ECO:0000250	469..471		0/1 (0%)
		Coenzyme A binding. /evidence=ECO:0000250	540..542		0/1 (0%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920