DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11407 and pdgy

DIOPT Version :9

Sequence 1:	NP_650831.1	Gene:	CG11407 / 42354	FlyBaseID:	FBgn0038733	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	NP_001188590.1	Gene:	pdgy / 32426	FlyBaseID:	FBgn0027601	Length:	597	Species:	Drosophila melanogaster

Alignment Length:	569	Identity:	138/569 - (24%)
Similarity:	240/569 - (42%)	Gaps:	57/569 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 RPASYYDADRKIWSGDQLEYY----FD----PHLSIGEIIFNEMRRHPQLIAQISATENTILTRA 60
            |..|..:.|:.:....:..||    ||    |::.:.|.::.:.::..:..|.:....:...|.|
  Fly    42 RTQSVSETDKFLHYSPEDGYYKTSPFDPVTIPNVPLHEYVWRDFKKWERRTAAVCVITDRQYTFA 106

  Fly    61 ELQ-ANAMHIASYMRSLGLLQMDIVGIIARNTTHISAVAYACFFNGIAFHSLNISYEQSTIEKLF 124
            ::: |:|...........|.:.|::.|...|..............|:...::|..|....|.:..
  Fly   107 QMRDASAAFAVRLQTKFNLQKPDVLAICLPNLPEYPIATLGAIEAGLTVTTVNPVYTPDEIARQL 171

  Fly   125 SITRPNIIFCDGDEFEKVRSAT----AQLDVKIITMRNH---PSGSIRIDQVLSTPIEKNFQPVR 182
            :.:....:......|..:..|:    .|:.:.::.....   |.|:|...::.||      |.||
  Fly   172 TFSGAKFLVGTVSGFATLSQASKLVGRQIPIAVVRTSAEEALPEGAIDFSELTST------QNVR 230

  Fly   183 LEQ-------GNDQTLAILCSSGTTGIPKAVTITNSRQILNSSHSLTTN----------DVQYSH 230
            .|.       ..|..:.:..||||||:||.|.:        |.:::|:|          |:....
  Fly   231 YEDLKAPKEASADDMVFLPFSSGTTGLPKGVML--------SHNNITSNCEQVQASLPLDLMGPQ 287

  Fly   231 STLD------WITGLLTTVTSGVFSTKRIIADNIFDPEFFMRLVEEHQITWIIQAPAHMAMMVNS 289
            :||.      .|.||...:.|.:....|:.....|.|:.|||.::::|.:.:...|.....|:|.
  Fly   288 NTLPGVLPFFHIYGLTVVMLSKLGQGCRLATMPCFKPDDFMRSLDKYQGSILNLVPPIALFMINH 352

  Fly   290 PSFTTSDLSSLRYYLFGGSRASVETQHRIRSRLSKDCLHFAYGFTELGSMAALNLHFDEKPNSVG 354
            |..|......|:..:.|.:........|..::.........||.||...:..|....::...|.|
  Fly   353 PKLTQETAPHLKVVMSGAAPIGQHDVERFLNKFPNTVFKQGYGMTEASPVVLLTPEGNKVYASTG 417

  Fly   355 RLVAGLKLKVICEKG---ESLGPDEVGELCLWNGQYWAGYYGNPEETHKMRDHHNWFHTGDLGYV 416
            .|.|..:.|::...|   :.:||...||||:...|..|||..|.|.........||..:||:.:.
  Fly   418 VLPASTEAKIVPLDGSDAKGVGPRTTGELCVRGPQVMAGYLNNDEANQVTFYPGNWLRSGDVAFY 482

  Fly   417 DDDGFIYIVERKKDMLKFQNIMYYPNEIESVISKMPDVVEVCVFGVWNEINGDEATAAVVKKRGS 481
            |:||..||.:|.|:::|.:.....|.|:|:|:...|.::|..|||:.:|.||:...|.||.::|.
  Fly   483 DEDGLFYITDRMKELIKVKGFQVPPAELEAVLRDHPKILEAAVFGIPHEFNGEAPRAIVVLRQGE 547

  Fly   482 ALTAQDIVDYVETHIDAKYKQLNGGAIIVEDLVRSPNGKTNRMANKAFF 530
            ..:|::|..||...: |.||:|.||.|.|:::.::|.||..|...|..|
  Fly   548 KASAEEISAYVAERV-AHYKKLEGGVIFVDEVPKNPTGKILRRELKEKF 595

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11407	NP_650831.1	CaiC	26..523	CDD:223395	129/534 (24%)
CG11407	NP_650831.1	Firefly_Luc_like	47..522	CDD:213279	126/508 (25%)
pdgy	NP_001188590.1	CaiC	77..595	CDD:223395	129/532 (24%)
pdgy	NP_001188590.1	Firefly_Luc_like	99..587	CDD:213279	125/502 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452140
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.815465	Normalized mean entropy	S2257
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24096
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.800