DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11407 and Slc27a5

DIOPT Version :9

Sequence 1:	NP_650831.1	Gene:	CG11407 / 42354	FlyBaseID:	FBgn0038733	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	NP_033538.2	Gene:	Slc27a5 / 26459	MGIID:	1347100	Length:	689	Species:	Mus musculus

Alignment Length:	520	Identity:	112/520 - (21%)
Similarity:	211/520 - (40%)	Gaps:	89/520 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 PQLIAQI-SATENTILTRAELQANAMHIASYMRSL---GLLQ--MDIVGIIARNTTHISAVAYAC 101
            |..:|.: :.:|.:.:|.::|.|.:...|..:::.   .::|  .|...|:...:..|||::
Mouse   127 PDRVALVCTGSEGSSITNSQLDARSCQAAWVLKAKLKDAVIQNTRDAAAILVLPSKTISALS--- 188

  Fly   102 FFNGIAFHSLNISY---EQSTIEKLFSI--TRPNIIFCDGDEFEKVRSATAQLDVKIITM----R 157
            .|.|:|.....:::   ....:..|.|:  :..:::..|.|..|.:.....:|..:.|..    .
Mouse   189 VFLGLAKLGCPVAWINPHSRGMPLLHSVRSSGASVLIVDPDLQENLEEVLPKLLAENIHCFYLGH 253

  Fly   158 NHPSGSIR-----IDQVLSTPIEKNFQPVRLEQGNDQTLAILCSSGTTGIPKAVTITNSRQILNS 217
            :.|:..:.     :|...|.|:..:   :|...........:.:|||||:||...:::.| ::..
Mouse   254 SSPTPGVEALGASLDAAPSDPVPAS---LRATIKWKSPAIFIFTSGTTGLPKPAILSHER-VIQV 314

  Fly   218 SHSLT-----TNDVQYS----HSTLDWITGLL-------TTVTSGVFSTKRIIADNIFDPEFFMR 266
            |:.|:     .:||.|.    :.|:..:.|.|       |.|.:..||..|..|:
Mouse   315 SNVLSFCGCRADDVVYDVLPLYHTIGLVLGFLGCLQVGATCVLAPKFSASRFWAE---------- 369

  Fly   267 LVEEHQITWIIQAPAHMAMMVNSPSFTTSDLSSLRYYLFGGSRASVETQHRIRSRLSKDCLHFAY 331
             ..:|.:|.|:.....:..:.|.|......:.::|..:..|.||:|  ....:.|.....:...|
Mouse   370 -CRQHGVTVILYVGEILRYLCNVPEQPEDKIHTVRLAMGNGLRANV--WKNFQQRFGPIRIWEFY 431

  Fly   332 GFTELGSMAALNLHFDEKPNSVGRLVAGLKL-------KVICEKGESLG-------PDEVGELCL 382
            |.|| |::..:|  :.....:|||....|::       :...|..|.|.       |.|.|:..|
Mouse   432 GSTE-GNVGLMN--YVGHCGAVGRTSCILRMLTPFELVQFDIETAEPLRDKQGFCIPVEPGKPGL 493

  Fly   383 W-----NGQYWAGYYGNPEETHK------MRDHHNWFHTGDLGYVDDDGFIYIVERKKDMLKFQN 436
            .     ..|.:.||.|:..|:::      .|....:|:|||:..:|.:||.|..:|..|..:::.
Mouse   494 LLTKVRKNQPFLGYRGSQAESNRKLVANVRRVGDLYFNTGDVLTLDQEGFFYFQDRLGDTFRWKG 558

  Fly   437 IMYYPNEIESVISKMPDVVEVCVFGVWNEINGDE---ATAAVVKKRGSALTAQDIVDYVETHIDA 498
            ......|:|.|:|.:..:.||.|:||  .:.|.|   ..|||....|.....|.:..:|.:.:.|
Mouse   559 ENVSTGEVECVLSSLDFLEEVNVYGV--PVPGCEGKVGMAAVKLAPGKTFDGQKLYQHVRSWLPA 621

Fly 499 498
Mouse 622 621

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11407	NP_650831.1	CaiC	26..523	CDD:223395	112/520 (22%)
CG11407	NP_650831.1	Firefly_Luc_like	47..522	CDD:213279	111/516 (22%)
Slc27a5	NP_033538.2	PRK08279	100..685	CDD:236217	112/520 (22%)
Slc27a5	NP_033538.2	AFD_class_I	139..679	CDD:302604	109/508 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839235
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930