DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11407 and Acsf3

DIOPT Version :9

Sequence 1:	NP_650831.1	Gene:	CG11407 / 42354	FlyBaseID:	FBgn0038733	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	NP_659181.2	Gene:	Acsf3 / 257633	MGIID:	2182591	Length:	583	Species:	Mus musculus

Alignment Length:	593	Identity:	127/593 - (21%)
Similarity:	218/593 - (36%)	Gaps:	105/593 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPYRPASYYDADRKIWSGDQLEYYFDPHLSIGEIIFNEMRRH---------------PQLIAQIS 50
            :|:|        |..||           |:..::|....|.|               |..|..::
Mouse     7 LPFR--------RLFWS-----------LASSQLIPRRHRGHSLLPTTPEAHTDGSVPVFIRALA 52

  Fly    51 ATENTIL-------TRAELQANAMHIASYMRSL-----GLLQMDIVGIIARNTTHISAVAYACFF 103
            ..:...|       |..||...::.:|..:..|     |.||.:.|..:..|........:|.:.
Mouse    53 FGDRIALIDKYGHHTYRELYDRSLCLAQEICRLQGCKVGDLQEERVSFLCSNDVSYVVAQWASWM 117

  Fly   104 NGIAFHSLNISYEQSTIEKLFSITRPNIIFCDGDEFEKVRSATAQLDVKIITMRNHPSGSIRIDQ 168
            :|.....|...:.::.:|.....:|.:::....:..|::.....:|.|.::     |........
Mouse   118 SGGVAVPLYWKHPEAQLEYFIQDSRSSLVVVGQEYLERLSPLAQRLGVPLL-----PLTPAVYHG 177

  Fly   169 VLSTPIEKNFQPVRLEQGNDQTLAILCSSGTTGIPKAVTITNSRQI------LNSSHSLTTNDVQ 227
            ....|.|   |||......|:...|..:|||||.||....|: |.:      |..|.:.|.|||.
Mouse   178 ATEKPTE---QPVEESGWRDRGAMIFYTSGTTGRPKGALSTH-RNLAAVVTGLVHSWAWTKNDVI 238

  Fly   228 YSHSTLDWITGLLTTVTSGVFSTKRIIADNIFDPEFFMRLV-------EEHQITWIIQAPAHMAM 285
            .....|..:.|::..:...::    :.|..:..|||..:.|       |..|||..:..|...:.
Mouse   239 LHVLPLHHVHGVVNKLLCPLW----VGATCVMLPEFSAQQVWEKFLSSEAPQITVFMAVPTVYSK 299

  Fly   286 MVN--SPSFTTSDLSS---------LRYYLFGGSRASVETQHRIRSRLSKDCLHFAYGFTELGSM 339
            :::  ...||...:..         :|..:.|.:...|....:.||......|. .||.||:|..
Mouse   300 LLDYYDKHFTQPHVQDFVRAVCKERIRLMVSGSAALPVPLLEKWRSATGHTLLE-RYGMTEIGMA 363

  Fly   340 AALNLHFDEKPNSVGRLVAGLKLKVIC----------------EKGESLGP---DEVGELCLWNG 385
            .:..|.....|.|||..:.|:::::|.                |:|..:.|   ::.|||.:...
Mouse   364 LSNPLTEARVPGSVGTPLPGVEVRIISENPQKGSPYIIHAEGNERGTKVTPGFEEKEGELLVRGP 428

  Fly   386 QYWAGYYGNPEETHKMRDHHNWFHTGDLGYVDDDGFIYIVERKKDMLKFQNIMYYPNEIESVISK 450
            ..:..|:..||||........||.|||.....|..:........|::|.........|||..:..
Mouse   429 SVFREYWDKPEETKSAFTSDGWFRTGDTAVFKDARYWIRGRTSVDIIKTGGYKVSALEIERHLLA 493

  Fly   451 MPDVVEVCVFGVWNEINGDEATAAVVKKRGSALTAQDIVDYVETHIDAKYKQLNGGAIIVEDLVR 515
            .|.:.:|.|.||.:...|...||.|..:.|.:|:..|:.::.. .:.|.| .:....::||::.|
Mouse   494 HPSITDVAVIGVPDMTWGQRVTAVVALQEGHSLSHGDLKEWAR-GVLAPY-AVPSELLLVEEIPR 556

  Fly   516 SPNGKTNR 523
            :..||.|:
Mouse   557 NQMGKVNK 564

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11407	NP_650831.1	CaiC	26..523	CDD:223395	121/566 (21%)
CG11407	NP_650831.1	Firefly_Luc_like	47..522	CDD:213279	115/529 (22%)
Acsf3	NP_659181.2	MCS	55..569	CDD:341264	116/526 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810