DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11407 and SPCC1827.03c

DIOPT Version :9

Sequence 1:	NP_650831.1	Gene:	CG11407 / 42354	FlyBaseID:	FBgn0038733	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	NP_001342732.1	Gene:	SPCC1827.03c / 2539253	PomBaseID:	SPCC1827.03c	Length:	512	Species:	Schizosaccharomyces pombe

Alignment Length:	515	Identity:	127/515 - (24%)
Similarity:	219/515 - (42%)	Gaps:	48/515 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 AQISATENTILTRAELQANAMHIASYMRSLGLLQMDIVGIIARNTTHISAVAYACFFNGIAFHSL 111
            |.::.:.|..|:.:||:...|.:...:.|||:...|.|.|...|........||..:.......|
pombe    18 ALVAPSLNAELSFSELRIAIMDLQRQIASLGIKVGDPVNIAIPNGLEFVVAFYAVSWQRAICGPL 82

  Fly   112 NISYEQSTIEKLFSITRPNIIFC-DGD---------EFEKVRSATAQL----DVKIITMRNHPSG 162
            |.:|:||..|......:..::.. :|.         ..:|:..|.|:|    ..:::.:.:....
pombe    83 NSNYKQSEFEFYIDDLKSKLVIVPEGSVAANTPAVRAAKKLSVAVAELAWCPKSRLVRIVHFEGA 147

  Fly   163 SIRIDQVLSTPIEKNFQPVRLEQGNDQTLAILCSSGTTGIPKAVTITNSRQILNSSHSLTTN--- 224
            .|...|.|..|     ||       |..:.:|.:|||||.||.|.:|: :.:..|.|::||:
pombe   148 KINAPQPLGLP-----QP-------DDVMLVLHTSGTTGRPKVVPLTH-KNLCRSIHNITTSYRL 199

  Fly   225 ---DVQYSHSTLDWITGLLTTVTSGVFSTKRIIADNIFDPEFFMRLVEEHQITWIIQAPAHMAMM 286
               |..|....|..:.|||..:.|.:.|....:....|....|.:...::..||....|....::
pombe   200 DPRDTSYVVMPLFHVHGLLCGLLSTLASGGCAVVPPKFSAHSFWKEFIQYGATWYTAVPTIHQIL 264

  Fly   287 VNSPSFTTSDLSSLRYYLFGGSRASVETQHRIRSRLSKDCLHFAYGFTELGSMAALN-----LHF 346
            :.:|  ....|..:|:.....|..:.....::.:......|. ||..||.......|     :|
pombe   265 LRTP--PPKPLPRIRFIRSCSSPLAPPVLSKLEATFRAPVLE-AYAMTEASHQMTTNPLPPLVH- 325

  Fly   347 DEKPNSVGRLVAGLKLKVICEKGESLGPDEVGELCLWNGQYWAGYYGNPEETHKMRDHHNWFHTG 411
              ||:|||: ..|::||::.:||..:...:.||:|:.......||..||...........:|.||
pombe   326 --KPHSVGK-PFGVELKILDQKGNEMPQGKEGEICVRGINVTKGYLNNPAANKSSFTKDRFFRTG 387

  Fly   412 DLGYVDDDGFIYIVERKKDMLKFQNIMYYPNEIESVISKMPDVVEVCVFGVWNEINGDEATAAVV 476
            |.|.:|.||:::|..|.|:::........|.||::|:.:.|||.|...|.|.:|..|.:..||:.
pombe   388 DEGKLDKDGYVFITGRIKELVNRGGEKISPAEIDAVLMQHPDVSEAVCFAVPDEKYGQDIQAAIN 452

  Fly   477 KKRGSALTAQDIVDYVETHIDAKYKQLNGGAIIVEDLVRSPNGKT-NRMANKAFFLEAKS 535
            ...|..:|.:.:.||:|..: |.:| :.......:.:.::..||. .|:...|||..:|:
pombe   453 PVAGKTVTPKQLHDYLEQKV-AAFK-IPKKFYFTDRIPKTATGKVQRRLVCDAFFNHSKA 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11407	NP_650831.1	CaiC	26..523	CDD:223395	122/501 (24%)
CG11407	NP_650831.1	Firefly_Luc_like	47..522	CDD:213279	122/500 (24%)
SPCC1827.03c	NP_001342732.1	FACL_fum10p_like	160..502	CDD:213292	92/358 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X778
TreeFam	0	0.000	Not matched by this tool.
	3	2.810