Protein Alignment CG11407 and ACSL4

DIOPT Version :9

• Sequence 1: NP_650831.1
• Gene: CG11407 / 42354
• FlyBaseID: FBgn0038733
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: XP_024308119.1
• Gene: ACSL4 / 2182
• HGNCID: 3571
• Length: 717
• Species: Homo sapiens
• Alignment Length: 629
• Identity: 132/629 - (20%)
• Similarity: 220/629 - (34%)
• Gaps: 166/629 - (26%)

  Fly     2 PYRPASYYD--ADRKIWSGDQLEYYFDPHL-------SIG--EIIF--NEMRRHPQLIAQISATE 53
            |||..:::|  |...|...|.|:..||..:       |:|  ||:.  |||:.:.::..::....
Human    64 PYRSVTHFDSLAVIDIPGADTLDKLFDHAVSKFGKKDSLGTREILSEENEMQPNGKVFKKLILGN 128

  Fly    54 NTILTRAELQANAMHIASYMRSLGLLQMDIVGIIARNTTHISAVAYACF-FN------------G 105
            ...:...|:.....:..|.:.:|||...:.:.|...........|..|| :|            .
Human   129 YKWMNYLEVNRRVNNFGSGLTALGLKPKNTIAIFCETRAEWMIAAQTCFKYNFPLVTLYATLGKE 193

  Fly   106 IAFHSLN---ISYEQSTIEKLFSITRPNIIFCDGDEFEKVRSATAQLDV-----------KIITM 156
            ...|.||   .||..:::|.|.|                 :..||.||:           |.|..
Human   194 AVVHGLNESEASYLITSVELLES-----------------KLKTALLDISCVKHIIYVDNKAINK 241

  Fly   157 RNHPSG----SIR-IDQVLSTPIEKNFQPVRLEQGNDQTLAILCSSGTTGIPKAVTITNSRQILN 216
            ..:|.|    |:: ::::.|.|......|.| ...:|..: ::.:||:||.||.|.:.:|..|..
Human   242 AEYPEGFEIHSMQSVEELGSNPENLGIPPSR-PTPSDMAI-VMYTSGSTGRPKGVMMHHSNLIAG 304

  Fly   217 SS------HSLTTNDVQYSHSTLDWI---TGLLTTVTSGV---FSTKRIIADNIFD--------- 260
            .:      ..|...|....:..|..:   |..::..|.|.   :|:...::|....
Human   305 MTGQCERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGYSSPLTLSDQSSKIKKGSKGDC 369

  Fly   261 -----------PEFFMRL-------VEE-----------------HQITWIIQAPAHMAMMVNSP 290
                       ||...|:       |:|                 .||.....||....::....
Human   370 TVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFKIGYDYKLEQIKKGYDAPLCNLLLFKKV 434

  Fly   291 SFTTSDLSSLRYYLFGGSRASVETQHRIRSRLSKDCLHFAYGFTELGSMAALNLHFDEKPNSVGR 355
            .....  .::|..|.||:..|.:| ||..:......:...||.||......:....|.....||.
Human   435 KALLG--GNVRMMLSGGAPLSPQT-HRFMNVCFCCPIGQGYGLTESCGAGTVTEVTDYTTGRVGA 496

  Fly   356 --LVAGLKLKVICEKGESLG--PDEVGELCLWNGQYWAGYYGNPEETHKMRDH------HNWFHT 410
              :...:|||...|.|.::.  |:..||:.:.......||:.|.|:|  ..|:      ..||.|
Human   497 PLICCEIKLKDWQEGGYTINDKPNPRGEIVIGGQNISMGYFKNEEKT--AEDYSVDENGQRWFCT 559

  Fly   411 GDLGYVDDDGFIYIVERKKDMLKFQNIMYYP-NEIESVISKMPDVVEVCVF-------------- 460
            ||:|....||.:.|::||||::|.|...|.. .::|:.:...|.:..:|.|
Human   560 GDIGEFHPDGCLQIIDRKKDLVKLQAGEYVSLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVP 624

  Fly   461 ---------------GVWNEI-NGDEATAAVVKKRGSALTAQDI 488
                           |.|.:| |.....|.::|:...|..|..:
Human   625 NQKRLTLLAQQKGVEGTWVDICNNPAMEAEILKEIREAANAMKL 668

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11407	NP_650831.1	CaiC	26..523	CDD:223395	123/603 (20%)
		Firefly_Luc_like	47..522	CDD:213279	115/571 (20%)
ACSL4	XP_024308119.1	LC-FACS_euk	127..714	CDD:213293	115/566 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148966
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930