DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11407 and acs-21

DIOPT Version :9

Sequence 1:	NP_650831.1	Gene:	CG11407 / 42354	FlyBaseID:	FBgn0038733	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	NP_503845.1	Gene:	acs-21 / 178751	WormBaseID:	WBGene00016849	Length:	517	Species:	Caenorhabditis elegans

Alignment Length:	524	Identity:	127/524 - (24%)
Similarity:	217/524 - (41%)	Gaps:	71/524 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 SATENTILTRAELQANAMHI-----------ASYMRSLG-----------LLQMDIVGIIARNTT 92
            ::..|.|:::|.||::...:           ..:::..|           :.:.|.|......||
Worm    20 TSAANNIISQANLQSDISKVLFIDDGRKITYGDFVQRAGQYATALTEKYKIKKGDRVMARVSKTT 84

  Fly    93 HISAVAYACFFNGIAFHSLNISYEQSTIEKLFSITRPNI-IFC--DGDE---FEKVRSATAQLD- 150
            ..:|:..||...|..:..:|.:..||.........:|:: |.|  |.|:   |::|.. |..:|
Worm    85 DTAALYAACLQIGALYVPVNPALTQSEAAHYVKDAKPSLWITCKDDADQIAMFQRVLK-TVCIDN 148

  Fly   151 -VKIITMRNHPSGSIRIDQVLSTPIEKNFQPVRLEQGNDQTLAILC-SSGTTGIPKAV-----TI 208
             |::|.           ::||:....|......:|.......|.:| :|||||.||..     .:
Worm   149 PVEVIN-----------EKVLADEAGKRKACTMIEHVEKSNAATICFTSGTTGAPKGAVLSHGAL 202

  Fly   209 TNSRQILNSSHSLTTNDVQYSHSTLDWITGLLTTVTSGVFSTKRIIADNIFDPEFFMRLVEEHQI 273
            ||:...|......|.|||......:....||..::...:||...:|....||.|...:.::  ..
Worm   203 TNNTNALVQEWGFTENDVNLHCLPIFHAHGLYFSLHCSLFSHSSVIWRPNFDAEDCSKHLK--NA 265

  Fly   274 TWIIQAPAHMAMMVNSPSFTTSDLSSLRYYLFGGSRASVETQHRIRSRLSKDCLHFAYGFTELGS 338
            |..:..|...:.::.:.:|.......:|.::.|.:..||.|......|..:..|. .||.||.|.
Worm   266 TVFMGVPTFYSRLLATNNFNKESFEKIRLFISGSAPLSVPTLEEFEKRTGQVILE-RYGMTEAGV 329

  Fly   339 MAALNLHFDEKPNSVGRLVAGLKLKVICEKGESLGPDEVGELCLWNGQYWAGYYGNPEETHKMRD 403
            :|:..|....|..:||:.:.|::.:|          .|.||:.:.:...::.|:.|||:|.:...
Worm   330 IASNPLKGKRKAGTVGQALKGVQCRV----------TENGEIEIKSDSIFSEYWKNPEKTKEEFT 384

  Fly   404 HHNWFHTGDLGYVDDDGFIYIVERKKDMLKFQNIMYYPNEIESVISKMPDVVEVCVFGVWNEING 468
            ...||.|||:|.:|.||::.|..|.|||:.......||.|||..|..:..|.|..|....:...|
Worm   385 EDGWFKTGDVGSLDKDGYLTIGGRSKDMIISGGENIYPKEIEDAIDSIEFVKESAVIAAPHPDFG 449

  Fly   469 DEATAAVVKK---RGSALTAQDIVDYVETHIDAKYKQLNGGAIIVEDLVRSPNGKTNR-----MA 525
            :...|.||.|   .......:|:::.:...: |||| :....|::|:|.|:...|..:     ..
Worm   450 EAVVAVVVPKNMVEDEQKFEEDLIEMLRKKL-AKYK-VPKKVILLEELPRNHITKVRKDILRASY 512

  Fly   526 NKAF 529
            ||.|
Worm   513 NKLF 516

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11407	NP_650831.1	CaiC	26..523	CDD:223395	124/511 (24%)
CG11407	NP_650831.1	Firefly_Luc_like	47..522	CDD:213279	124/510 (24%)
acs-21	NP_503845.1	MCS	38..505	CDD:213307	119/493 (24%)
acs-21	NP_503845.1	PRK07514	40..517	CDD:181011	122/504 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810