DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11407 and acs-7

DIOPT Version :9

Sequence 1:	NP_650831.1	Gene:	CG11407 / 42354	FlyBaseID:	FBgn0038733	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	NP_495979.1	Gene:	acs-7 / 174472	WormBaseID:	WBGene00007228	Length:	540	Species:	Caenorhabditis elegans

Alignment Length:	554	Identity:	157/554 - (28%)
Similarity:	262/554 - (47%)	Gaps:	49/554 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 IWSGDQLEYYFDPHLSIGEIIFNEMRRH----PQLIAQISA-TENTILTRAELQANAMHIASYMR 74
            |:.|:|||.:..|   :.|::....:.|    |..:|.::| .|:..|...:|....:.|:.:..
Worm     2 IFHGEQLENHDKP---VHEVLLERFKVHQEKDPDNVAFVTAENEDDSLGFQQLGKKVLQISEWFV 63

  Fly    75 SLGLLQMDIVGIIARNTTHISAVAYACFFNGI-------AFHSLNISYEQSTIEKLFSITRPNII 132
            ..|..:.|:..:.:.|.....|.|...:..|:       .|.|..::|:   ||.    ::..:|
Worm    64 ENGYKKGDVFLLASYNNWRCFAAALGAWRAGLIVSAAASQFTSFEMNYQ---IED----SQSQVI 121

  Fly   133 FCDGDEFEKVRSATAQLDV--KIITM-RNHPSGSIRIDQVLSTPIEKNFQPVRLEQGNDQTLAIL 194
            ..|......|:.|...|..  :||:: .|.||..|:.| ||::.:.:|.:...::..|| .:.:.
Worm   122 LVDKHTLPVVQEACKNLKFVKQIISISANPPSPVIKFD-VLTSRLVRNLKMPLIDPKND-IVFLP 184

  Fly   195 CSSGTTGIPKAVTIT--NSRQILNSSHSLTTNDVQYSHSTLDWI-------------TGLLTTVT 244
            .||||||.||.|.|:  |...:|.||......:.:......|::             .|:..|:.
Worm   185 YSSGTTGKPKGVMISHLNFSMMLESSLRFFDANAKAIGLPPDFVLPYDLHFLPMYHAMGMFRTLL 249

  Fly   245 SGVFSTKRIIADNIFDPEFFMRLVEEHQITWIIQAPAHMAMMVNSPSFTTSDLSSLRYYLFGGSR 309
            :....|.:|:... ||.|..::.:|::.|..:...||....|:|||.....|:|||.....|.:.
Worm   250 TSYRGTTQIMFTK-FDMELMLKNIEKYSIMVLSLVPAIAVRMLNSPLLQKYDVSSLVSVTVGSAP 313

  Fly   310 ASVETQHRIRSRLSKDCLHFAYGFTELGSMAALNLHFDEKPN-SVGRLVAGLKLKVICEKGESLG 373
            .......:::..|....:...||.|||  ..|.:|.....|: ||||||.|..:||..|.|...|
Worm   314 FPESASKKLKQLLPNVNIVQGYGMTEL--TFATHLQSPGSPDGSVGRLVPGTSMKVKKEDGTLCG 376

  Fly   374 PDEVGELCLWNGQYWAGYYGNPEETHKMRDHHNWFHTGDLGYVDDDGFIYIVERKKDMLKFQNIM 438
            |.|:|||.:...|...||:...::|:::.|.|.:..|||:.|.|.:|..:|.:|.|:::|.....
Worm   377 PHEIGELWIKGPQMMKGYWKKEQQTNELLDEHGFMRTGDIVYFDKNGETFICDRIKELIKVNAKQ 441

  Fly   439 YYPNEIESVISKMPDVVEVCVFGVWNEINGDEATAAVVKKRGSAL-TAQDIVDYVETHIDAKYKQ 502
            ..|.|:||||.:..||.:||||||.:..:|:...|.||.|||..: |::.|:.::...: |:||.
Worm   442 VAPAELESVILEHDDVADVCVFGVDDASSGERPVACVVSKRGRDMETSKAIMKHINQKL-ARYKH 505

  Fly   503 LNGGAIIVEDLVRSPNGKTNRMANKAFFLEAKSS 536
            :. ....|.:::|:..||..|.|.|..||:||.:
Worm   506 IK-EIEFVSEIMRTGTGKLLRRAMKKAFLDAKKA 538

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11407	NP_650831.1	CaiC	26..523	CDD:223395	145/528 (27%)
CG11407	NP_650831.1	Firefly_Luc_like	47..522	CDD:213279	141/502 (28%)
acs-7	NP_495979.1	CaiC	12..540	CDD:223395	152/544 (28%)
acs-7	NP_495979.1	Firefly_Luc_like	35..524	CDD:213279	141/502 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.815465	Normalized mean entropy	S2257
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24096
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.870