DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11391 and CMR2

DIOPT Version :9

Sequence 1:	NP_650830.1	Gene:	CG11391 / 42353	FlyBaseID:	FBgn0038732	Length:	542	Species:	Drosophila melanogaster
Sequence 2:	NP_014736.1	Gene:	CMR2 / 854260	SGDID:	S000005619	Length:	1648	Species:	Saccharomyces cerevisiae

Alignment Length:	191	Identity:	39/191 - (20%)
Similarity:	68/191 - (35%)	Gaps:	42/191 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 DLNG--NPATSYDPVQKVWSGCSRHSLYNEELTVGQIIFRQLQRQPQRIFQISHTDNTRLTRFQM 65
            ||.|  |...|| .|::|:.....|||.|:...|.: .|::.:....:|...|...........|
Yeast  1089 DLKGLVNIIQSY-KVKRVFVDAKLHSLLNDNNVVNK-CFKKYKSLIPKITVFSKVKTKNALTVSM 1151

  Fly    66 LQNAAKIGCYLRDQGFKKETDLVGLMARNSTHVGALAYGCLFNGTPFHAVNPNLE----HNTISS 126
            .:|..|       |.|.         |:..|.:|...  |:......:.|..|:.    |:::.:
Yeast  1152 FKNVLK-------QKFG---------AKPGTRIGMTP--CVVWVNTEYDVTSNIHVTMTHSSLLN 1198

  Fly   127 LYKITRPRI----------LCCDTADYEKIKDIGASLGALIITVNGKLPGVISVADILQNP 177
            ..||.:..:          :|..|:      .:|.....|:....|....:.|:.|:|.:|
Yeast  1199 ASKIVKETLQLRNNSPLFSICSHTS------GLGFMFSCLLGIYTGASTCLFSLTDVLTDP 1253

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11391	NP_650830.1	CaiC	24..541	CDD:223395	31/168 (18%)
CG11391	NP_650830.1	AFD_class_I	51..527	CDD:302604	24/141 (17%)
CMR2	NP_014736.1	DMAP_binding	5..121	CDD:368923
		AFD_class_I	179..893	CDD:418409
		Dip2	1004..1626	CDD:341231	39/191 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900