DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11391 and 4CL2

DIOPT Version :9

Sequence 1:	NP_650830.1	Gene:	CG11391 / 42353	FlyBaseID:	FBgn0038732	Length:	542	Species:	Drosophila melanogaster
Sequence 2:	NP_188761.1	Gene:	4CL2 / 821678	AraportID:	AT3G21240	Length:	556	Species:	Arabidopsis thaliana

Alignment Length:	488	Identity:	129/488 - (26%)
Similarity:	225/488 - (46%)	Gaps:	39/488 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 KIGCYLRDQGFKKETDLVGLMARNSTHVGALAYGCLFNGTPFHAVNPNLEHNTISSLYKITRPRI 135
            |:...|.:.|.|:. |:|.::..||..|........|.|....:.||......||...|.:..::
plant    75 KLAAGLHNLGVKQH-DVVMILLPNSPEVVLTFLAASFIGAITTSANPFFTPAEISKQAKASAAKL 138

  Fly   136 LCCDTADYEKIKDIGASLGALIITVNG-KLP-GVISVADILQ------NPLPDDYEPAQFQRGVD 192
            :...:...:|||:: .:.|.||:|.:. .:| ..:..:::.|      :.:|:...|       :
plant   139 IVTQSRYVDKIKNL-QNDGVLIVTTDSDAIPENCLRFSELTQSEEPRVDSIPEKISP-------E 195

  Fly   193 RTMAILCSSGTTGTPKAVTLSNSRKLFEM---------HSYLGSDDVQYA--PSTLDWLTGLITL 246
            ..:|:..||||||.||.|.|::...:..:         :.|...|||...  |....:....|.|
plant   196 DVVALPFSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFNRDDVILCVLPMFHIYALNSIML 260

  Fly   247 VTAAVFGTVRLISSEMFSTAHFLDICEQHEVSWTIMANSHVAMLANCPKTSAQKLRSLKHLLFAG 311
            .:..|..|:.::..  |.....|:..::.:|:..::....|..:|..|:|....|.|:: ::.:|
plant   261 CSLRVGATILIMPK--FEITLLLEQIQRCKVTVAMVVPPIVLAIAKSPETEKYDLSSVR-MVKSG 322

  Fly   312 GHCLVATLKKMQSFLHGSGILRNAYGLTEVGTLVSYNYDTQSKPTSV-----GRLMANIRVKIVD 371
            ...|...|:...|....:..|...||:||.|.:::.:.....:|..|     |.::.|..:||:|
plant   323 AAPLGKELEDAISAKFPNAKLGQGYGMTEAGPVLAMSLGFAKEPFPVKSGACGTVVRNAEMKILD 387

  Fly   372 -SSGQLQGPKGLGEILCHNGQPWSGYVGNPLATAEMRDSAGWYHTGDVGYFDEDHYLHIVERKKD 435
             .:|........|||.....|...||:.:|||||...|..||.||||||:.|:|..|.||:|.|:
plant   388 PDTGDSLPRNKPGEICIRGNQIMKGYLNDPLATASTIDKDGWLHTGDVGFIDDDDELFIVDRLKE 452

  Fly   436 MLKYLGMMYYPHEVEEVIAQMPDVAEVCVFGIFRETEGDAAAASVVLRSGSKLDPKHVEQYVRKN 500
            ::||.|....|.|:|.::...|::.:|.|..:..|..|:...|.||....|.:....::|:|.|.
plant   453 LIKYKGFQVAPAELESLLIGHPEINDVAVVAMKEEDAGEVPVAFVVRSKDSNISEDEIKQFVSKQ 517

  Fly   501 VSVQFKHLHGGVQFVPQLAKSANGKVNRQAVKA 533
            | |.:|.:: .|.|...:.|:.:||:.|:.::|
plant   518 V-VFYKRIN-KVFFTDSIPKAPSGKILRKDLRA 548

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11391	NP_650830.1	CaiC	24..541	CDD:223395	129/488 (26%)
CG11391	NP_650830.1	AFD_class_I	51..527	CDD:302604	127/480 (26%)
4CL2	NP_188761.1	PLN02246	14..553	CDD:215137	129/488 (26%)
4CL2	NP_188761.1	4CL	32..546	CDD:213272	128/484 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24096
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920