DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11391 and Slc27a2

DIOPT Version :9

Sequence 1:	NP_650830.1	Gene:	CG11391 / 42353	FlyBaseID:	FBgn0038732	Length:	542	Species:	Drosophila melanogaster
Sequence 2:	NP_113924.2	Gene:	Slc27a2 / 65192	RGDID:	71103	Length:	620	Species:	Rattus norvegicus

Alignment Length:	545	Identity:	118/545 - (21%)
Similarity:	222/545 - (40%)	Gaps:	95/545 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 TVGQIIFRQLQRQPQRIFQISHTDNTRLTRFQMLQNAAKIGCYLRDQGFKKETDLVGLMARNSTH 97
            |:..:...|.::.|.:.| :...|.| ||..|:.:.:.::...|.|....::.|.|.|...|...
  Rat    54 TILHVFLEQARKTPHKPF-LLFRDET-LTYAQVDRRSNQVARALHDHLGLRQGDCVALFMGNEPA 116

  Fly    98 VGALAYGCLFNGTPFHAVNPNLEHNTISSLYKITRPRILCCDTADYEKIKDIGASL-----GALI 157
            ...|..|.|..|.|...:|.|:...::...::....::|......:|.::::..:|     ....
  Rat   117 YVWLWLGLLKLGCPMACLNYNIRAKSLLHCFQCCGAKVLLASPELHEAVEEVLPTLKKEGMSVFY 181

  Fly   158 ITVNGKLPGVISVAD----ILQNPLPDDYE-------PAQFQRGVDRTMAILCSSGTTGTPKAVT 211
            ::......||.:|.|    :..:|:|:.:.       ||.:          :.:|||||.|||.|
  Rat   182 VSRTSNTNGVDTVLDKVDGVSADPIPESWRSEVTFTTPAVY----------IYTSGTTGLPKAAT 236

  Fly   212 LSNSRKLF----EMHSYLGSDDVQYAPSTLDWLTGL-ITLVTAAVFGTVRLISSEMFSTAHFLDI 271
            :::.|..:    .:.|.:.:.||.|....|.....| |.|....|.|....:.|: ||.:.|.|.
  Rat   237 INHHRLWYGTSLALRSGIKAHDVIYTTMPLYHSAALMIGLHGCIVVGATFALRSK-FSASQFWDD 300

  Fly   272 CEQHEVSWTIMANSHVAMLANCPKTSAQKLRSLKHLLFAG--GHCLVATLKKMQSFLHGSGILRN 334
            |.::..:........:..|.|.|:....:...:|..|..|  |......:|:.     |...:..
  Rat   301 CRKYNATVIQYIGELLRYLCNTPQKPNDRDHKVKIALGNGLRGDVWREFIKRF-----GDIHIYE 360

  Fly   335 AYGLTEVGTLVSYNYDTQSKPTSVGRLMAN--IRVKIV----------------DSSGQ-LQGPK 380
            .|..|| |.:...||     |..:|.:...  ::.|:|                |::|. ::.||
  Rat   361 FYASTE-GNIGFMNY-----PRKIGAVGRENYLQKKVVRHELIKYDVEKDEPVRDANGYCIKVPK 419

  Fly   381 G-LGEILCHNGQ--PWSGYVGNPLAT--AEMRD--SAG--WYHTGDVGYFDEDHYLHIVERKKDM 436
            | :|.::|...:  |:.||.|....|  .::||  ..|  ::::||:...|.:::::..:|..|.
  Rat   420 GEVGLLICKITELTPFFGYAGGKTQTEKKKLRDVFKKGDVYFNSGDLLMIDRENFIYFHDRVGDT 484

  Fly   437 LKYLGMMYYPHEVEEVIAQMPDVAEVCVFGI-FRETEGDAAAASVVLR-----SGSKLDPKHVEQ 495
            .::.|......||.:::..:..|.||.|:|: ....||....||:.::     :|.||. :|:.:
  Rat   485 FRWKGENVATTEVADIVGLVDFVEEVNVYGVPVPGHEGRIGMASIKMKENYEFNGKKLF-QHISE 548

  Fly   496 YVRK-------------NVSVQFKH 507
            |:..             .::..|||
  Rat   549 YLPSYSRPRFLRIQDTIEITGTFKH 573

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11391	NP_650830.1	CaiC	24..541	CDD:223395	118/545 (22%)
CG11391	NP_650830.1	AFD_class_I	51..527	CDD:302604	114/527 (22%)
Slc27a2	NP_113924.2	hsFATP2a_ACSVL_like	74..610	CDD:341261	114/524 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342947
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840